SCHEMBL1264136

SCHEMBL1264136

O=C1NC(=O)C(C2CCCCC2)C(=O)N1

nearest known ligand 0.69

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.69
MAP3K14 Q99558 1/20 0.44
ALDH1A1 P00352 1/20 0.32
TSHR P16473 1/20 0.31
MAOA P21397 1/20 0.30
MAOB P27338 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7640738 0.98 MAPT (0.65) MAPTMAP3K14ALDH1A1TSHR
SCHEMBL1981593 0.93 MAPT (0.59) MAPTMAP3K14TSHR
SCHEMBL25406504 0.87 MAPT (0.52) MAPTMAP3K14TSHR
SCHEMBL21677137 0.80 MAPT (0.62) MAPTMAP3K14
SCHEMBL4005170 0.76 MAPT (0.44) MAPT
SCHEMBL7061475 0.73 MAPT (0.44) MAPTALDH1A1TSHR
SCHEMBL9402183 0.73 MAPT (0.44) MAPTALDH1A1TSHR
SCHEMBL16640292 0.73 MAPT (0.44) MAPTALDH1A1TSHR
Biphenyl SCHEMBL27978117 0.71 MAPT (0.42) MAPTMAP3K14ALDH1A1
SCHEMBL11280497 0.71 MAPT (0.52) MAPTMAP3K14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 260 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9668943-B2 Dental conditioning composition KABUSHIKI KAISHA SHOFU (JP) 2017-06-06 US claimed
US-6784224-B2 STORAGE STABLE, GELATION INHIBITION, CONSISTS OF (METH)ACRYLATE MONOMERS, A FILLER AND A PYRIMIDINETRIONES CATALYST; MULTI-PASTES CONTAINS DIFFERENT COMPONENTS, MIXED WITH EACH OTHER TO POLYMERIZE; DENTAL ADHESIVES GC CORPORATION (JP) 2004-08-31 US claimed
US-20260144715-A1 DENTAL CURABLE COMPOSITION HAVING HIGH MECHANICAL STRENGTH SHOFU INC. (JP) 2026-05-28 US disclosed
US-12622847-B2 Organosilicon compound and dental composition containing same KURARAY NORITAKE DENTAL INC. (JP) 2026-05-12 US disclosed
EP-4717251-A2 DENTAL CURABLE COMPOSITION HAVING HIGH MECHANICAL STRENGTH Shofu Inc. (JP) 2026-04-01 EP disclosed
US-20260069510-A1 DENTAL RESIN-REINFORCED GLASS IONOMER CEMENT COMPOSITION SHOFU INC. (JP) 2026-03-12 US disclosed
EP-3733152-B1 POWDER-LIQUID TYPE RESIN-REINFORCED DENTAL GLASS IONOMER CEMENT COMPOSITION SHOFU INC (JP) 2026-03-11 EP disclosed
US-20260060900-A1 DENTAL COMPOSITE RESIN KIT SHOFU INC. (JP) 2026-03-05 US disclosed
EP-4659729-A1 DENTAL RESIN-REINFORCED GLASS IONOMER CEMENT COMPOSITION Shofu Inc. (JP) 2025-12-10 EP disclosed
US-12465559-B2 Fluorescent curable dental composition and cured product thereof KURARAY NORITAKE DENTAL INC. (JP) 2025-11-11 US disclosed
US-20250213434-A1 DENTAL CURABLE COMPOSITION HAVING FAVORABLE COLOR COMPATIBILITY KURARAY NORITAKE DENTAL INC. (JP) 2025-07-03 US disclosed
EP-0702948-B1 TOOTH SURFACE TREATING AGENT SHOFU KK (JP) 2001-03-07 EP disclosed
EP-1066813-A2 Dental adhesive composition KABUSHIKI KAISHA SHOFU (JP) 2001-01-10 EP disclosed
EP-1056432-A1 IMPROVED CATALYTIC POLYMERIZATION ACCELERATOR SYSTEMS Mycone Dental Supply Company, Inc. (US) 2000-12-06 EP disclosed
WO-1999043288-A1 IMPROVED CATALYTIC POLYMERIZATION ACCELERATOR SYSTEMS MYCONE DENTAL SUPPLY COMPANY, INC. (US) 1999-09-02 WO disclosed
US-5883153-A SUSTAINED RELEASE GLASS IONOMERS SHOFU INC. (JP) 1999-03-16 US disclosed
US-5707611-A Tooth surface treating agent KABUSHIKI KAISHA SHOFU (JP) 1998-01-13 US disclosed
EP-0702948-A1 TOOTH SURFACE TREATMENT KABUSHIKI KAISHA SHOFU (JP) 1996-03-27 EP disclosed
EP-0694298-A1 PREFORMED GLASS IONOMER FILLER WHICH CAN SUSTAINEDLY RELEASE FLUORIDE ION AND DENTAL COMPOSITION CONTAINING THE SAME SHOFU INC. (JP) 1996-01-31 EP disclosed
US-5264513-A Dental adhesive KABUSHIKI KAISHA SHOFU (JP) 1993-11-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260069510-A1 DENTAL RESIN-REINFORCED GLASS IONOMER CEMENT COMPOSITION GRIN3A, HBG1, ASIC1 MAPT 2952/4885MAP3K14 4622/4885ALDH1A1 3441/4885
US-20260060900-A1 DENTAL COMPOSITE RESIN KIT BOLA2; BOLA2B, LBR, COL2A1 MAPT 2976/4885MAP3K14 3522/4885ALDH1A1 314/4885
US-12465559-B2 Fluorescent curable dental composition and cured product thereof BRD1, TBCA, BAZ1A MAPT 1437/4885MAP3K14 4259/4885ALDH1A1 1780/4885
US-20260144715-A1 DENTAL CURABLE COMPOSITION HAVING HIGH MECHANICAL STRENGTH CAD, SMCHD1, ITGA1 MAPT 991/4885MAP3K14 2315/4885ALDH1A1 1523/4885
US-12622847-B2 Organosilicon compound and dental composition containing same MSL1, ITGA1, ITGAL MAPT 4304/4885MAP3K14 4195/4885ALDH1A1 668/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.