Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TET2 | Q6N021 | 2/20 | 0.50 |
| ▸ | CA2 | P00918 | 11/20 | 0.41 |
| ▸ | CA1 | P00915 | 8/20 | 0.40 |
| ▸ | CA9 | Q16790 | 6/20 | 0.40 |
| ▸ | CA3 | P07451 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.39 |
| ▸ | CA12 | O43570 | 3/20 | 0.39 |
| ▸ | CA7 | P43166 | 2/20 | 0.39 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.39 |
| ▸ | LDHA | P00338 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | CA6 | P23280 | 1/20 | 0.38 |
| ▸ | CA5A | P35218 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.38 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2777606 | 1.00 | TET2 (0.50) | TET2CA2CA1CA9CA3 | |
| SCHEMBL18688250 | 0.83 | TET2 (0.50) | TET2CA2CA1CA9CA3 | |
| SCHEMBL26386116 | 0.79 | CCR2 (0.42) | TET2PTGS2RAD51 | |
| SCHEMBL13799680 | 0.79 | TRPV4 (0.39) | TET2CA2RAD51 | |
| SCHEMBL29556118 | 0.78 | PTGS1 (0.48) | TET2CA2CA1CA9PTGS2 | |
| SCHEMBL789994 | 0.78 | PTGS1 (0.48) | TET2CA2CA1CA9PTGS2 | |
| SCHEMBL30049401 | 0.77 | CA2 (0.44) | TET2CA2CA1CA9PTGS2 | |
| Hydrochloric Acid SCHEMBL29968814 | 0.77 | PTGS1 (0.47) | TET2CA2CA1CA9PTGS2 | |
| Iodide SCHEMBL28547721 | 0.77 | PTGS1 (0.47) | TET2CA2CA1CA9PTGS2 | |
| SCHEMBL3781004 | 0.77 | CA2 (0.50) | TET2CA2CA1CA9CA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024115549-A1 | ARYL- AND HETEROARYL-SULFONAMIDE DERIVATIVES AS CCR8 MODULATORS | IDORSIA PHARMACEUTICALS LTD (CH) | 2024-06-06 | — | — | WO | claimed |
| WO-2024115549-A1 | ARYL- AND HETEROARYL-SULFONAMIDE DERIVATIVES AS CCR8 MODULATORS | IDORSIA PHARMACEUTICALS LTD (CH) | 2024-06-06 | — | — | WO | disclosed |