Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.70 |
| ▸ | MAPT | P10636 | 6/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.70 |
| ▸ | AGTR1 | P30556 | 3/20 | 0.70 |
| ▸ | GAA | P10253 | 3/20 | 0.70 |
| ▸ | HPGD | P15428 | 4/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL733998 | 0.84 | EPHX1 (0.55) | ALDH1A1MAPTSMN1; SMN2AGTR1GAA | |
| SCHEMBL21518479 | 0.84 | ALDH1A1 (0.58) | ALDH1A1MAPTSMN1; SMN2AGTR1GAA | |
| SCHEMBL15933411 | 0.81 | ALDH1A1 (0.53) | ALDH1A1MAPTSMN1; SMN2AGTR1GAA | |
| SCHEMBL11443282 | 0.81 | ALDH1A1 (0.48) | ALDH1A1MAPTSMN1; SMN2AGTR1GAA | |
| SCHEMBL4312066 | 0.81 | THRA (0.52) | ALDH1A1MAPTSMN1; SMN2AGTR1GAA | |
| Hydrochloric Acid SCHEMBL11158946 | 0.80 | SMN1; SMN2 (0.63) | ALDH1A1MAPTSMN1; SMN2HPGDMAPK1 | |
| SCHEMBL11449465 | 0.79 | ALDH1A1 (0.47) | ALDH1A1MAPTSMN1; SMN2AGTR1GAA | |
| SCHEMBL14053181 | 0.79 | ALDH1A1 (0.62) | ALDH1A1MAPTSMN1; SMN2AGTR1GAA | |
| SCHEMBL29894695 | 0.79 | FABP4 (0.56) | ALDH1A1MAPTSMN1; SMN2LMNATSHR | |
| SCHEMBL2728813 | 0.79 | FABP4 (0.56) | ALDH1A1MAPTSMN1; SMN2LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4662206-A1 | GSPT1 DEGRADER COMPOUNDS | Captor Therapeutics S.A. (PL) | 2025-12-17 | — | — | EP | disclosed |
| WO-2024165577-A1 | GSPT1 DEGRADER COMPOUNDS | CAPTOR THERAPEUTICS S.A. (PL) | 2024-08-15 | — | — | WO | disclosed |
| WO-2024167423-A1 | GSPT1 DEGRADER COMPOUNDS | CAPTOR THERAPEUTICS S.A. (PL) | 2024-08-15 | — | — | WO | disclosed |