Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 5/20 | 0.53 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.53 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | NAMPT | P43490 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31043597 | 1.00 | OPRK1 (0.53) | OPRK1OPRM1OPRD1ALDH1A1KDM4E | |
| SCHEMBL31043970 | 0.94 | OPRK1 (0.52) | OPRK1OPRM1OPRD1ALDH1A1KDM4E | |
| SCHEMBL31029084 | 0.94 | OPRK1 (0.52) | OPRK1OPRM1OPRD1ALDH1A1KDM4E | |
| SCHEMBL31029080 | 0.91 | LMNA (0.58) | OPRK1OPRM1OPRD1ALDH1A1KDM4E | |
| SCHEMBL31043584 | 0.91 | OPRK1 (0.63) | OPRK1OPRM1OPRD1ALDH1A1KDM4E | |
| SCHEMBL31043697 | 0.91 | LMNA (0.58) | OPRK1OPRM1OPRD1ALDH1A1KDM4E | |
| SCHEMBL31029220 | 0.91 | OPRK1 (0.63) | OPRK1OPRM1OPRD1ALDH1A1KDM4E | |
| SCHEMBL31029055 | 0.87 | OPRK1 (0.51) | OPRK1OPRM1OPRD1ALDH1A1KDM4E | |
| SCHEMBL31029133 | 0.87 | OPRK1 (0.51) | OPRK1OPRM1OPRD1ALDH1A1KDM4E | |
| SCHEMBL31029109 | 0.84 | OPRK1 (0.56) | OPRK1OPRM1OPRD1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4638433-A1 | NAMPT MODULATORS | Cytokinetics, Inc. (US) | 2025-10-29 | — | — | EP | disclosed |
| US-20240279215-A1 | NAMPT MODULATORS | CYTOKINETICS, INCORPORATED | 2024-08-22 | — | — | US | disclosed |
| WO-2024137981-A1 | NAMPT MODULATORS | CYTOKINETICS, INCORPORATED (US) | 2024-06-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240279215-A1 | NAMPT MODULATORS | NAMPT, SIRT1, NNT | OPRK1 3011/4885OPRM1 3013/4885OPRD1 2558/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.