Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | THRB | P10828 | 2/20 | 0.36 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.36 |
| ▸ | RORC | P51449 | 1/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.35 |
| ▸ | FEN1 | P39748 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.35 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.35 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.35 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31639417 | 0.86 | MAPT (0.44) | ALDH1A1MAPTLMNATHRBRORC | |
| SCHEMBL31158852 | 0.85 | SMN1; SMN2 (0.40) | RORCGPR119ALOX5APFEN1SMN1; SMN2 | |
| SCHEMBL31158858 | 0.82 | APP (0.42) | MAPTRORCGPR119ALOX5APFEN1 | |
| SCHEMBL31159140 | 0.80 | PDK2 (0.40) | RORCGPR119KMT2AALOX5APFEN1 | |
| SCHEMBL10036179 | 0.79 | PDK4 (0.51) | ALDH1A1MAPTLMNA | |
| SCHEMBL29535433 | 0.79 | PDK4 (0.51) | ALDH1A1MAPTLMNA | |
| SCHEMBL31334845 | 0.78 | ALDH1A1 (0.45) | ALDH1A1MAPTLMNATHRBGPR119 | |
| SCHEMBL22179574 | 0.77 | ALDH1A1 (0.51) | ALDH1A1MAPTLMNATHRBKMT2A | |
| SCHEMBL31548463 | 0.77 | ALDH1A1 (0.51) | ALDH1A1MAPTLMNATHRBKMT2A | |
| SCHEMBL31029044 | 0.76 | MAPT (0.46) | ALDH1A1MAPTLMNATHRBRORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4638433-A1 | NAMPT MODULATORS | Cytokinetics, Inc. (US) | 2025-10-29 | — | — | EP | disclosed |
| WO-2024137981-A1 | NAMPT MODULATORS | CYTOKINETICS, INCORPORATED (US) | 2024-06-27 | — | — | WO | disclosed |