Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 1/20 | 0.40 |
| ▸ | GRM5 | P41594 | 1/20 | 0.40 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.40 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.40 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.39 |
| ▸ | FEN1 | P39748 | 1/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | JAK1 | P23458 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | RORC | P51449 | 7/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.36 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.36 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31158852 | 0.85 | SMN1; SMN2 (0.40) | PDK2GRM5GRM1ALOX5APFEN1 | |
| SCHEMBL31158858 | 0.82 | APP (0.42) | PDK2ALOX5APFEN1GPR119JAK2 | |
| SCHEMBL31159182 | 0.82 | GPR119 (0.48) | PDK2PDK4GPR119JAK2JAK1 | |
| SCHEMBL31029069 | 0.80 | ALDH1A1 (0.47) | PDK2ALOX5APFEN1GPR119RORC | |
| SCHEMBL31159047 | 0.79 | MMP13 (0.40) | ALOX5APFEN1GPR119JAK2JAK1 | |
| SCHEMBL3642418 | 0.77 | PDK4 (0.55) | PDK2GRM5GRM1PDK4GPR119 | |
| SCHEMBL31158870 | 0.75 | KIF11 (0.41) | ALOX5APFEN1GPR119RORC | |
| SCHEMBL31159014 | 0.75 | GPR119 (0.45) | GRM5GRM1PDK4GPR119RORC | |
| SCHEMBL3642397 | 0.75 | PDK4 (0.68) | GRM5GRM1PDK4JAK1 | |
| SCHEMBL3642252 | 0.75 | PDK4 (0.47) | PDK2GRM5GRM1PDK4GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024201248-A1 | COMPOUNDS AND METHODS FOR DEGRADING GSPT1 | PIN THERAPEUTICS, INC. (KR) | 2024-10-03 | — | — | WO | disclosed |