Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.40 |
| ▸ | FEN1 | P39748 | 1/20 | 0.40 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | RORC | P51449 | 5/20 | 0.38 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.37 |
| ▸ | BUB1 | O43683 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31158858 | 0.87 | APP (0.42) | ALOX5APFEN1GPR119RORCPDK2 | |
| SCHEMBL31159140 | 0.85 | PDK2 (0.40) | ALOX5APFEN1GPR119RORCPDK2 | |
| SCHEMBL31029069 | 0.85 | ALDH1A1 (0.47) | SMN1; SMN2ALOX5APFEN1GPR119RORC | |
| SCHEMBL31159047 | 0.80 | MMP13 (0.40) | ALOX5APFEN1HDAC2GPR119HDAC1 | |
| SCHEMBL31159143 | 0.76 | HDAC2 (0.51) | HDAC2HDAC1RORCGRM5GRM1 | |
| SCHEMBL13993111 | 0.76 | GRM1 (0.57) | GRM5GRM1 | |
| SCHEMBL31158870 | 0.76 | KIF11 (0.41) | ALOX5APFEN1HDAC2GPR119HDAC1 | |
| SCHEMBL25603154 | 0.76 | NR1H2 (0.39) | ALOX5APFEN1HDAC2GPR119HDAC1 | |
| SCHEMBL31158783 | 0.75 | USP30 (0.47) | MKNK1HDAC2GPR119HDAC1RORC | |
| SCHEMBL31159014 | 0.74 | GPR119 (0.45) | SMN1; SMN2GPR119RORCGRM5GRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024201248-A1 | COMPOUNDS AND METHODS FOR DEGRADING GSPT1 | PIN THERAPEUTICS, INC. (KR) | 2024-10-03 | — | — | WO | disclosed |