Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.57 |
| ▸ | CA1 | P00915 | 5/20 | 0.52 |
| ▸ | CA2 | P00918 | 5/20 | 0.52 |
| ▸ | BTK | Q06187 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 3/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | NFE2L2 | Q16236 | 4/20 | 0.45 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | S100A4 | P26447 | 1/20 | 0.41 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.41 |
| ▸ | FEN1 | P39748 | 1/20 | 0.41 |
| ▸ | CA5A | P35218 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29705304 | 0.85 | NFE2L2 (0.52) | PTGES2CA1CA2BTKCA9 | |
| SCHEMBL789817 | 0.85 | NFE2L2 (0.52) | PTGES2CA1CA2BTKCA9 | |
| SCHEMBL7038996 | 0.83 | PTGES2 (0.47) | PTGES2CA1CA2CA9MAPK1 | |
| SCHEMBL31598828 | 0.83 | PTGES2 (0.47) | PTGES2CA1CA2CA9MAPK1 | |
| SCHEMBL15212419 | 0.81 | PTGES2 (0.46) | PTGES2CA1CA2CA9NFE2L2 | |
| SCHEMBL15211939 | 0.79 | PTGES2 (0.45) | PTGES2CA1CA2CA9NFE2L2 | |
| SCHEMBL30613857 | 0.79 | PTGES2 (0.44) | PTGES2CA1CA2CA9ALOX5AP | |
| SCHEMBL21494394 | 0.79 | PTGES2 (0.44) | PTGES2CA1CA2CA9ALOX5AP | |
| Formic Acid SCHEMBL14247346 | 0.78 | NFE2L2 (0.50) | PTGES2CA1CA2CA9MAPK1 | |
| Formic Acid SCHEMBL31344342 | 0.78 | NFE2L2 (0.50) | PTGES2CA1CA2CA9MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250145589-A1 | PYRIDINE DERIVATIVE AND USE THEREOF | SICHUAN HUIYU PHARMACEUTICAL CO., LTD. (CN) | 2025-05-08 | — | — | US | disclosed |
| EP-4406948-A1 | PYRIDINE DERIVATIVE AND USE THEREOF | Sichuan Huiyu Pharmaceutical Co., Ltd. (CN) | 2024-07-31 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250145589-A1 | PYRIDINE DERIVATIVE AND USE THEREOF | KRAS, NRAS, BRAF | PTGES2 3075/4885CA1 3768/4885CA2 3676/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.