Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 1.00 |
| ▸ | LMNA | P02545 | 3/20 | 1.00 |
| ▸ | POLB | P06746 | 2/20 | 1.00 |
| ▸ | MAPT | P10636 | 2/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 2/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 1.00 |
| ▸ | HPGD | P15428 | 2/20 | 1.00 |
| ▸ | HTT | P42858 | 1/20 | 1.00 |
| ▸ | MCL1 | Q07820 | 1/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 1.00 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 1.00 |
| ▸ | BCHE | P06276 | 1/20 | 0.68 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.66 |
| ▸ | PTPRCAP | Q14761 | 2/20 | 0.61 |
| ▸ | TDP2 | O95551 | 1/20 | 0.54 |
| ▸ | RAD52 | P43351 | 1/20 | 0.54 |
| ▸ | CASP6 | P55212 | 1/20 | 0.54 |
| ▸ | DRD2 | P14416 | 4/20 | 0.50 |
| ▸ | DRD1 | P21728 | 3/20 | 0.49 |
| ▸ | HTR2C | P28335 | 3/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Actinodaphnine SCHEMBL30477775 | 1.00 | KDM4E (1.00) | KDM4ELMNAPOLBMAPTKMT2A | |
| Actinodaphnine SCHEMBL29596257 | 1.00 | KDM4E (1.00) | KDM4ELMNAPOLBMAPTKMT2A | |
| Actinodaphnine SCHEMBL2450424 | 1.00 | KDM4E (1.00) | KDM4ELMNAPOLBMAPTKMT2A | |
| SCHEMBL29390321 | 0.92 | KDM4E (0.84) | KDM4ELMNAPOLBMAPTKMT2A | |
| SCHEMBL31029804 | 0.83 | PTPRCAP (0.76) | KDM4ELMNAPOLBMAPTKMT2A | |
| SCHEMBL11891033 | 0.83 | KDM4E (0.71) | KDM4ELMNAPOLBMAPTKMT2A | |
| Cassythine SCHEMBL27858889 | 0.83 | ALDH1A1 (0.71) | KDM4ELMNAPOLBMAPTKMT2A | |
| SCHEMBL5325477 | 0.82 | ALDH1A1 (0.70) | KDM4ELMNAPOLBMAPTKMT2A | |
| SCHEMBL31029778 | 0.82 | KDM4E (0.70) | KDM4ELMNAPOLBMAPTKMT2A | |
| Launobine SCHEMBL28948970 | 0.82 | KDM4E (0.69) | KDM4ELMNAPOLBMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023121486-A1 | COMPOSITIONS AND COMPOUNDS FOR TREATING COVID-19 | INTERNATIONAL PATENT HOLDINGS LLC (KN) | 2023-06-29 | — | — | WO | claimed |
| US-8067401-B2 | Compounds and compositions for treating infection | INTERNATIONAL PATENT HOLDINGS LLC (KN) | 2011-11-29 | — | — | US | claimed |
| US-20090069277-A1 | Compounds and compositions for treating infection | INTERNATIONAL PATENT HOLDINGS LTD. | 2009-03-12 | — | — | US | claimed |
| WO-2023121486-A1 | COMPOSITIONS AND COMPOUNDS FOR TREATING COVID-19 | INTERNATIONAL PATENT HOLDINGS LLC (KN) | 2023-06-29 | — | — | WO | disclosed |
| US-8697660-B2 | Compounds and compositions for treating infection | INTERNATIONAL PATENT HOLDINGS LLC | 2014-04-15 | — | — | US | disclosed |
| US-20130023487-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING INFECTION | INTERNATIONAL PATENT HOLDINGS LLC (KN) | 2013-01-24 | — | — | US | disclosed |
| US-20120190734-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING INFECTION | INTERNATIONAL PATENT HOLDINGS LLC (KN) | 2012-07-26 | — | — | US | disclosed |
| US-8067401-B2 | Compounds and compositions for treating infection | INTERNATIONAL PATENT HOLDINGS LLC (KN) | 2011-11-29 | — | — | US | disclosed |
| US-8067401-B2 | Compounds and compositions for treating infection | INTERNATIONAL PATENT HOLDINGS LLC (KN) | 2011-11-29 | — | — | US | disclosed |
| US-20090069277-A1 | Compounds and compositions for treating infection | INTERNATIONAL PATENT HOLDINGS LTD. | 2009-03-12 | — | — | US | disclosed |
| US-20090069277-A1 | Compounds and compositions for treating infection | INTERNATIONAL PATENT HOLDINGS LTD. | 2009-03-12 | — | — | US | disclosed |
| US-20090069277-A1 | Compounds and compositions for treating infection | INTERNATIONAL PATENT HOLDINGS LTD. | 2009-03-12 | — | — | US | disclosed |
| WO-2007134485-A1 | APORPHINE AND OXOAPORPHINE COMPOUNDS AND PHARMACEUTICAL USE THEREOF | LOTUS PHARMACEUTICAL CO., LTD. (CN) | 2007-11-29 | — | — | WO | disclosed |
| US-7294715-B2 | Aporphine and oxoaporphine compounds and pharmaceutical use thereof | LOTUS PHARMACEUTICAL CO., LTD. (TW) | 2007-11-13 | — | — | US | disclosed |
| US-20060211723-A1 | Aporphine and oxoaporphine compounds and pharmaceutical use thereof | LOTUS PHARMACEUTICAL CO., LTD. (TW) | 2006-09-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120190734-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING INFECTION | RPN2, LSS, CLIC4 | KDM4E 715/4885LMNA 4592/4885POLB 1879/4885 |
| US-20130023487-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING INFECTION | RPN2, LSS, CLIC4 | KDM4E 715/4885LMNA 4592/4885POLB 1879/4885 |
| US-20090069277-A1 | Compounds and compositions for treating infection | RPN2, LSS, CLIC4 | KDM4E 715/4885LMNA 4592/4885POLB 1879/4885 |
| US-20060211723-A1 | Aporphine and oxoaporphine compounds and pharmaceutical use thereof | OGFRL1, THOP1, APOL1 | KDM4E 4464/4885LMNA 2135/4885POLB 2996/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.