Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 7/20 | 0.39 |
| ▸ | VDR | P11473 | 3/20 | 0.39 |
| ▸ | THRB | P10828 | 7/20 | 0.38 |
| ▸ | MITF | O75030 | 1/20 | 0.37 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31030181 | 0.83 | SMN1; SMN2 (0.39) | NPC1RAB9AMAPTSMN1; SMN2KMT2A | |
| SCHEMBL31030173 | 0.76 | CA12 (0.44) | THRAVDRTHRBMAPTVCAM1 | |
| SCHEMBL31469012 | 0.75 | THRA (0.31) | THRAVDRTHRB | |
| SCHEMBL31030183 | 0.74 | TSHR (0.46) | MAPTVCAM1 | |
| SCHEMBL31030198 | 0.73 | MAPT (0.36) | NPC1RAB9AMAPTSMN1; SMN2KMT2A | |
| SCHEMBL18158924 | 0.67 | MAPT (0.38) | MITFNPC1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL9251220 | 0.66 | JAK2 (0.42) | THRAVDRNPC1RAB9AMAPT | |
| SCHEMBL24257931 | 0.65 | SMN1; SMN2 (0.47) | NPC1SMN1; SMN2KMT2A | |
| SCHEMBL27415994 | 0.63 | EPHX2 (0.42) | — | |
| SCHEMBL27292565 | 0.62 | MEN1 (0.41) | NPC1RAB9AMAPTSMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4651907-A1 | DRUG CONJUGATES AND METHODS OF PREPARING AND USING THE SAME | Adcentrx Therapeutics Inc. (US) | 2025-11-26 | — | — | EP | disclosed |
| WO-2024155761-A1 | DRUG CONJUGATES AND METHODS OF PREPARING AND USING THE SAME | ADCENTRX THERAPEUTICS INC. (US) | 2024-07-25 | — | — | WO | disclosed |