Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.38 |
| ▸ | LMNA | P02545 | 5/20 | 0.38 |
| ▸ | MEN1 | O00255 | 5/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.38 |
| ▸ | HTT | P42858 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | MITF | O75030 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18158922 | 0.77 | PSMD14 (0.42) | MAPTLMNAMEN1KMT2AHTT | |
| SCHEMBL31030181 | 0.76 | SMN1; SMN2 (0.39) | MAPTLMNAMEN1KMT2AHTT | |
| SCHEMBL31030198 | 0.74 | MAPT (0.36) | MAPTLMNAMEN1KMT2AHTT | |
| SCHEMBL31030192 | 0.68 | MAPT (0.43) | MAPTLMNAMEN1KMT2AHTT | |
| SCHEMBL31030201 | 0.67 | THRA (0.39) | MAPTKMT2ASMN1; SMN2NPC1MITF | |
| SCHEMBL24257931 | 0.67 | SMN1; SMN2 (0.47) | MEN1KMT2ASMN1; SMN2HPGDNPC1 | |
| SCHEMBL18158928 | 0.67 | CLPP (0.33) | MAPTLMNAMEN1KMT2AHTT | |
| SCHEMBL16260534 | 0.66 | LMNA (0.48) | MAPTLMNAMEN1KMT2AHTT | |
| SCHEMBL22297332 | 0.66 | TSHR (0.41) | MEN1KMT2AHTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL21906800 | 0.66 | TSHR (0.41) | MEN1KMT2AHTTSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160304459-A1 | NOVEL COMPOUND, PRODUCTION METHOD THEREFOR, AND APPLICATION THEREFOR | TOKYO UNIVERSITY OF PHARMACY & LIFE SCIENCES (JP) | 2016-10-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160304459-A1 | NOVEL COMPOUND, PRODUCTION METHOD THEREFOR, AND APPLICATION THEREFOR | VIP, MRPL21, THEM6 | MAPT 3717/4885LMNA 4478/4885MEN1 514/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.