Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 8/20 | 0.60 |
| ▸ | MVD | P53602 | 2/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.44 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.44 |
| ▸ | ITGAV | P06756 | 1/20 | 0.44 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.44 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.44 |
| ▸ | REN | P00797 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | F2 | P00734 | 1/20 | 0.43 |
| ▸ | LTA4H | P09960 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | PEPD | P12955 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4728479 | 0.79 | THRB (0.49) | ACETHRBALOX12KMT2AITGB3 | |
| SCHEMBL6407009 | 0.79 | ACE (0.60) | ACETHRBALOX12KMT2AITGB3 | |
| SCHEMBL9728258 | 0.79 | ACE (0.53) | ACETHRBALOX12KMT2AITGB3 | |
| SCHEMBL17285637 | 0.76 | ACE (0.51) | ACETHRBALOX12KMT2AITGB3 | |
| SCHEMBL11303640 | 0.76 | ACE (1.00) | ACEMVDRENLMNAHSD17B10 | |
| SCHEMBL4902901 | 0.75 | RAB9A (0.56) | ACEITGB3ITGB1ITGAVITGA5 | |
| SCHEMBL2422749 | 0.74 | ACE (0.48) | ACETHRBALOX12KMT2AITGB3 | |
| SCHEMBL2422744 | 0.74 | ACE (0.48) | ACETHRBALOX12KMT2AITGB3 | |
| SCHEMBL17285592 | 0.74 | ACE (0.48) | ACETHRBALOX12KMT2AITGB3 | |
| SCHEMBL11304977 | 0.73 | ACE (1.00) | ACEMVDREN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100247463-A1 | N-(PHOSPHONOALKYL)-AMINO ACIDS, DERIVATIVES THEREOF AND COMPOSITIONS AND METHODS OF USE | YU RUEY J | 2010-09-30 | — | — | US | claimed |