Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.61 |
| ▸ | EGFR | P00533 | 1/20 | 0.61 |
| ▸ | TP53 | P04637 | 1/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
| ▸ | PKM | P14618 | 1/20 | 0.61 |
| ▸ | HPGD | P15428 | 1/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.61 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.61 |
| ▸ | JAK1 | P23458 | 1/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | CES2 | O00748 | 1/20 | 0.55 |
| ▸ | CES1 | P23141 | 1/20 | 0.55 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12382427 | 0.84 | CES2 (0.57) | MEN1KMT2AKDM4EALDH1A1EGFR | |
| SCHEMBL6505231 | 0.79 | CES2 (0.61) | MEN1KMT2AKDM4EALDH1A1EGFR | |
| SCHEMBL28660594 | 0.79 | CES2 (0.52) | MEN1KMT2AKDM4EALDH1A1EGFR | |
| SCHEMBL6010034 | 0.77 | HDAC1 (0.71) | KDM4EALOX15HSD17B10CES2CES1 | |
| SCHEMBL31305702 | 0.77 | HDAC1 (0.71) | KDM4EALOX15HSD17B10CES2CES1 | |
| SCHEMBL497521 | 0.77 | NPC1 (0.57) | MEN1KMT2AKDM4EALDH1A1CYP3A4 | |
| SCHEMBL7765340 | 0.76 | KDM4E (0.53) | MEN1KMT2AKDM4EALDH1A1EGFR | |
| SCHEMBL3416759 | 0.76 | KMT2A (0.57) | MEN1KMT2AKDM4EALDH1A1EGFR | |
| SCHEMBL761366 | 0.76 | PLAU (0.66) | MEN1KMT2AKDM4ECES2CES1 | |
| SCHEMBL1149678 | 0.76 | NPC1 (0.62) | MEN1KMT2AKDM4EALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118653158-A | Synthesis and application of 4-oxo-oxazoline compound | 西北师范大学 | 2024-09-17 | — | — | CN | disclosed |