Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 13/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 13/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 5/20 | 0.41 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | BMPR2 | Q13873 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4293328 | 0.77 | FLT3 (0.48) | FGFR1HSD17B10GAANPC1ALDH1A1 | |
| SCHEMBL4282464 | 0.76 | CHEK2 (0.44) | FGFR1HSD17B10GAANPC1ALDH1A1 | |
| SCHEMBL30358449 | 0.74 | CYP2C9 (0.37) | IDO1KCNH2CYP2C9 | |
| SCHEMBL22862454 | 0.71 | GAA (0.53) | IDO1KCNH2FGFR1HSD17B10GAA | |
| SCHEMBL29490273 | 0.71 | GAA (0.53) | IDO1KCNH2FGFR1HSD17B10GAA | |
| SCHEMBL30497277 | 0.70 | HSD17B10 (0.53) | IDO1KCNH2CYP2C9FGFR1HSD17B10 | |
| SCHEMBL11171 | 0.70 | SMN1; SMN2 (0.50) | FGFR1HSD17B10GAANPC1ALDH1A1 | |
| SCHEMBL31196606 | 0.69 | IDO1 (0.52) | IDO1KCNH2CYP2C9ALDH1A1 | |
| SCHEMBL30497269 | 0.69 | GAA (0.70) | FGFR1HSD17B10GAANPC1ALDH1A1 | |
| SCHEMBL4287769 | 0.68 | GAA (0.57) | FGFR1HSD17B10GAANPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4651877-A1 | INHIBITORS OF ACTIVIN RECEPTOR TYPE 1 (ACVR1) AND ACTIVIN RECEPTOR LIKE TYPE 1 (ACVRL1), AND METHODS USING SAME | Baylor College of Medicine (US) | 2025-11-26 | — | — | EP | disclosed |
| WO-2024155715-A1 | INHIBITORS OF ACTIVIN RECEPTOR TYPE 1 (ACVR1) AND ACTIVIN RECEPTOR LIKE TYPE 1 (ACVRL1), AND METHODS USING SAME | BAYLOR COLLEGE OF MEDICINE (US) | 2024-07-25 | — | — | WO | disclosed |