SCHEMBL11171

SCHEMBL11171

Cn1cnc2ccc(C(N)=O)cc21

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 3/20 0.50
ALDH1A1 P00352 2/20 0.50
KDM4E B2RXH2 1/20 0.50
BRD4 O60885 1/20 0.50
BRPF1 P55201 1/20 0.50
HSD17B10 Q99714 1/20 0.50
FGFR1 P11362 2/20 0.49
DYRK1A Q13627 1/20 0.49
CHRNA7 P36544 1/20 0.47
KMT2A Q03164 3/20 0.45
NPC1 O15118 2/20 0.45
TP53 P04637 2/20 0.45
RAB9A P51151 2/20 0.45
GAA P10253 1/20 0.45
HPGD P15428 1/20 0.45
MAPT P10636 1/20 0.44
HSD11B1 P28845 2/20 0.44
CHEK2 O96017 1/20 0.43
TNKS O95271 1/20 0.43
TNKS2 Q9H2K2 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1299105 0.87 FGFR1 (0.60) SMN1; SMN2ALDH1A1KDM4EBRD4BRPF1
SCHEMBL1869730 0.85 FGFR1 (0.60) SMN1; SMN2ALDH1A1HSD17B10FGFR1DYRK1A
SCHEMBL16602284 0.85 ALDH1A1 (0.53) SMN1; SMN2ALDH1A1FGFR1DYRK1ACHRNA7
SCHEMBL29819602 0.85 ALDH1A1 (0.53) SMN1; SMN2ALDH1A1FGFR1DYRK1ACHRNA7
SCHEMBL20570515 0.83 CHRNA7 (0.47) SMN1; SMN2ALDH1A1FGFR1DYRK1ACHRNA7
SCHEMBL7362182 0.83 F10 (0.49) SMN1; SMN2DYRK1ACHRNA7KMT2ANPC1
SCHEMBL3491023 0.83 CHRNA7 (0.53) SMN1; SMN2ALDH1A1KDM4EFGFR1DYRK1A
Carbamic Acid SCHEMBL3412931 0.82 ALDH1A1 (0.50) SMN1; SMN2ALDH1A1KDM4EFGFR1DYRK1A
SCHEMBL18229473 0.81 FGFR1 (0.50) SMN1; SMN2ALDH1A1KDM4EBRD4BRPF1
SCHEMBL3492748 0.81 FGFR1 (0.53) SMN1; SMN2ALDH1A1KDM4EFGFR1DYRK1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250381202-A1 PRODRUG KIT FOR MULTI-PRONGED CHEMOTHERAPY ZOUNEK ALEX (DE) 2025-12-18 US disclosed
EP-4536656-A1 BICYCLIC-SUBSTITUTED GLUTARIMIDE CEREBLON BINDERS C4 Therapeutics, Inc. (US) 2025-04-16 EP disclosed
WO-2024263963-A2 COMPOSITIONS COMPRISING ANTINEOPLASTONS AND METHODS OF TREATING HEAD AND NECK CANCER BURZYNSKI STANISLAW R (US) 2024-12-26 WO disclosed
EP-4398904-A1 SELECTED COMPOUNDS FOR TARGETED DEGRADATION OF BRD9 C4 Therapeutics, Inc. (US) 2024-07-17 EP disclosed
WO-2024105144-A1 QUINAZOLINONE COMPOUND AS BRAF INHIBITOR FOR THE TREATMENT OF ADVANCED SOLID CANCER OR METASTASES F. HOFFMANN-LA ROCHE AG (CH) 2024-05-23 WO disclosed
WO-2023239750-A1 BICYCLIC-SUBSTITUTED GLUTARIMIDE CEREBLON BINDERS C4 THERAPEUTICS, INC. (US) 2023-12-14 WO disclosed
CN-116723839-A Tricyclic heterobifunctional compounds for degrading target proteins C4医药公司 2023-09-08 CN disclosed
EP-4228625-A1 TRICYCLIC HETEROBIFUNCTIONAL COMPOUNDS FOR DEGRADATION OF TARGETED PROTEINS C4 Therapeutics, Inc. (US) 2023-08-23 EP disclosed
EP-4228639-A1 TRICYCLIC LIGANDS FOR DEGRADATION OF IKZF2 OR IKZF4 C4 Therapeutics, Inc. (US) 2023-08-23 EP disclosed
EP-4228624-A1 TRICYCLIC COMPOUNDS TO DEGRADE NEOSUBSTRATES FOR MEDICAL THERAPY C4 Therapeutics, Inc. (US) 2023-08-23 EP disclosed
WO-2019191112-A1 CEREBLON BINDERS FOR THE DEGRADATION OF IKAROS C4 THERAPEUTICS, INC. (US) 2019-10-03 WO disclosed
WO-2018237026-A1 N/O-LINKED DEGRONS AND DEGRONIMERS FOR PROTEIN DEGRADATION C4 THERAPEUTICS, INC. (US) 2018-12-27 WO disclosed
WO-2018209155-A1 EXTENDED RELEASE MICROPARTICLES AND SUSPENSIONS THEREOF FOR MEDICAL THERAPY Graybug Vision, Inc. (US) 2018-11-15 WO disclosed
EP-3373978-A1 AGGREGATING MICROPARTICLES FOR THERAPY Graybug Vision, Inc. (US) 2018-09-19 EP disclosed
WO-2017083779-A1 AGGREGATING MICROPARTICLES FOR THERAPY Graybug Vision, Inc. (US) 2017-05-18 WO disclosed
EP-2791101-A1 TREATMENT OF INFLAMMATION Vascular Biogenics Ltd. (IL) 2014-10-22 EP disclosed
WO-2014074805-A1 SELECTIVE TARGETING OF CANCER STEM CELLS WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH (US) 2014-05-15 WO disclosed
WO-2013088245-A1 TREATMENT OF INFLAMMATION VASCULAR BIOGENICS LTD. (IL) 2013-06-20 WO disclosed
EP-2493310-A1 BENZIMIDAZOLES AS FATTY ACID SYNTHASE INHIBITORS GlaxoSmithKline LLC (US) 2012-09-05 EP disclosed
WO-2011056635-A1 BENZIMIDAZOLES AS FATTY ACID SYNTHASE INHIBITORS GLAXOSMITHKLINE LLC (US) 2011-05-12 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250381202-A1 PRODRUG KIT FOR MULTI-PRONGED CHEMOTHERAPY KIT, CTSL, PAICS SMN1; SMN2 4104/4885ALDH1A1 1779/4885KDM4E 2995/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.