Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 1/20 | 0.45 |
| ▸ | CUL4A | Q13619 | 1/20 | 0.36 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.35 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.35 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.35 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.35 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.35 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.35 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.35 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.35 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.35 |
| ▸ | MAPK8 | P45983 | 9/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25824093 | 1.00 | IKBKB (0.45) | IKBKBCUL4AGRIN2DGRIN3BGRIA1 | |
| SCHEMBL25824021 | 0.88 | HTR3E (0.40) | IKBKBCUL4AGRIN2DGRIN3BGRIA1 | |
| SCHEMBL8102963 | 0.84 | CUL4A (0.51) | IKBKBCUL4AMAPK8KDM4EALDH1A1 | |
| SCHEMBL24832295 | 0.82 | IKBKB (0.45) | IKBKBCUL4AGRIN2DGRIN3BGRIA1 | |
| SCHEMBL121472 | 0.82 | HTR3E (0.45) | IKBKBCUL4AGRIN2DGRIN3BGRIA1 | |
| SCHEMBL13077027 | 0.82 | IKBKB (0.66) | IKBKBMAPK8KDM4EALDH1A1POLB | |
| SCHEMBL17895298 | 0.78 | IKBKB (0.42) | IKBKB | |
| SCHEMBL30578099 | 0.78 | MAPK8 (0.54) | IKBKBMAPK8KDM4EALDH1A1GLA | |
| SCHEMBL120846 | 0.78 | MAPK8 (0.54) | IKBKBMAPK8KDM4EALDH1A1GLA | |
| SCHEMBL8118650 | 0.78 | GRIN2D (0.49) | IKBKBGRIN2DGRIN3BGRIA1GRIA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118359617-A | Protein arginine methyltransferase inhibitors | 华润医药研究院（深圳）有限公司 | 2024-07-19 | — | — | CN | disclosed |
| CN-118359604-A | Protein arginine methyltransferase inhibitors | 华润医药研究院（深圳）有限公司 | 2024-07-19 | — | — | CN | disclosed |