SCHEMBL31031273

SCHEMBL31031273

CN(C)Cc1nccn1CCOCCOCCOCCOCCOCCN=[N+]=[N-]

nearest known ligand 0.40

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
MGMT P16455 1/20 0.40
OPRM1 P35372 1/20 0.31
OPRD1 P41143 1/20 0.31
OPRK1 P41145 1/20 0.31
MMP2 P08253 1/20 0.30
MMP9 P14780 1/20 0.30
MMP8 P22894 1/20 0.30
MMP13 P45452 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31031282 0.81 MGMT (0.34) MGMT
SCHEMBL9866875 0.78 ADORA2A (0.34)
SCHEMBL17723266 0.75 MGMT (0.38) MGMT
SCHEMBL28782143 0.72 CA12 (0.44) MGMT
SCHEMBL30660189 0.66 RAB9A (0.47)
SCHEMBL9866983 0.65 ADORA2A (0.33)
SCHEMBL25721178 0.65 CA12 (0.40) MGMT
SCHEMBL31031287 0.65 CA12 (0.40) MGMT
SCHEMBL31031275 0.64 ALDH1A1 (0.49) MGMT
SCHEMBL27983649 0.64 SMN1; SMN2 (0.48)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4652160-A1 COMPOUNDS FOR NUCLEIC ACID CLEAVAGE Cambridge Enterprise Limited (GB) 2025-11-26 EP disclosed
WO-2024153950-A1 COMPOUNDS FOR NUCLEIC ACID CLEAVAGE CAMBRIDGE ENTERPRISE LIMITED (GB) 2024-07-25 WO disclosed
WO-2024153952-A1 COMPOUNDS FOR NUCLEIC ACID CLEAVAGE CAMBRIDGE ENTERPRISE LIMITED (GB) 2024-07-25 WO disclosed