Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9866983 | 0.85 | ADORA2A (0.33) | ADORA2AADORA2BKMT2AALDH1A1POLB | |
| SCHEMBL13587988 | 0.83 | TLR8 (0.39) | ADORA2AADORA2BKMT2AALDH1A1POLB | |
| SCHEMBL9866166 | 0.82 | ALDH1A1 (0.36) | ADORA2AADORA2BKMT2AALDH1A1POLB | |
| SCHEMBL8367322 | 0.82 | ADORA2A (0.36) | ADORA2AADORA2BKMT2AALDH1A1RAB9A | |
| SCHEMBL9867170 | 0.81 | ALDH1A1 (0.38) | ADORA2AADORA2BKMT2AALDH1A1POLB | |
| Hydrochloric Acid SCHEMBL8151433 | 0.81 | TLR8 (0.36) | ADORA2AADORA2BKMT2AALDH1A1POLB | |
| SCHEMBL9866859 | 0.80 | ALDH1A1 (0.37) | KMT2AALDH1A1POLBHRH3 | |
| SCHEMBL10446524 | 0.79 | ADORA2A (0.33) | ADORA2AADORA2BKMT2AALDH1A1POLB | |
| SCHEMBL31031273 | 0.78 | MGMT (0.40) | — | |
| SCHEMBL30660189 | 0.78 | RAB9A (0.47) | KMT2AALDH1A1RAB9AL3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5011838-A | Antiallergens, antihistamines | DOMPE FARMACEUTICI S.P.A. (IT) | 1991-04-30 | — | — | US | disclosed |
| EP-0397615-A2 | Pharmacologically active 2-substituted 3-(2-ethoxyethyl) imidazo [4,5-b] pyridines and pharmaceutical compositions containing them | DOMPE' FARMACEUTICI S.p.A. (IT) | 1990-11-14 | — | — | EP | disclosed |