Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN2 | P17706 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
| ▸ | ACE | P12821 | 3/20 | 0.43 |
| ▸ | MME | P08473 | 2/20 | 0.43 |
| ▸ | ECE1 | P42892 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.42 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.42 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.42 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.42 |
| ▸ | HPGDS | O60760 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3103171 | 1.00 | PTPN2 (0.47) | PTPN2PTPN1ACEMMEECE1 | |
| SCHEMBL3098759 | 0.86 | LAP3 (0.56) | PTPN1MMEECE1MEN1KMT2A | |
| SCHEMBL3098754 | 0.86 | LAP3 (0.56) | PTPN1MMEECE1MEN1KMT2A | |
| SCHEMBL2996598 | 0.86 | MME (0.56) | ACEMMEECE1MEN1KMT2A | |
| SCHEMBL2989598 | 0.86 | MME (0.56) | ACEMMEECE1MEN1KMT2A | |
| SCHEMBL5269150 | 0.81 | PTPN2 (0.49) | PTPN2PTPN1ACECA1CA12 | |
| SCHEMBL5269145 | 0.81 | PTPN2 (0.49) | PTPN2PTPN1ACECA1CA12 | |
| SCHEMBL2992789 | 0.81 | BACE1 (0.48) | MMEECE1MEN1KMT2ACA1 | |
| SCHEMBL27743729 | 0.81 | BACE1 (0.48) | MMEECE1MEN1KMT2ACA1 | |
| SCHEMBL3090770 | 0.81 | ACE (0.44) | PTPN2PTPN1ACEMMECA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100247463-A1 | N-(PHOSPHONOALKYL)-AMINO ACIDS, DERIVATIVES THEREOF AND COMPOSITIONS AND METHODS OF USE | YU RUEY J | 2010-09-30 | — | — | US | claimed |