Sugi Predict

Sugi Predict / Compounds / SCHEMBL3098754

SCHEMBL3098754

SCHEMBL3098754

NC(=O)C(Cc1ccccc1)NCP(=O)(O)O

nearest known ligand 0.56

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ LAP3 P28838 3/20 0.56
▸ ANPEP P15144 1/20 0.56
▸ MME P08473 1/20 0.50
▸ ECE1 P42892 1/20 0.50
▸ MEN1 O00255 1/20 0.50
▸ KMT2A Q03164 1/20 0.50
▸ HPGDS O60760 2/20 0.47
▸ PTPN1 P18031 1/20 0.46
▸ EPHX1 P07099 1/20 0.46
▸ ACP3 P15309 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3098759 1.00 LAP3 (0.56) LAP3ANPEPMMEECE1MEN1
SCHEMBL43350 0.87 MME (0.62) LAP3ANPEPMMEECE1MEN1
SCHEMBL43351 0.87 MME (0.62) LAP3ANPEPMMEECE1MEN1
SCHEMBL3103171 0.86 PTPN2 (0.47) MMEECE1MEN1KMT2AHPGDS
SCHEMBL3103180 0.86 PTPN2 (0.47) MMEECE1MEN1KMT2AHPGDS
SCHEMBL3100693 0.85 ERAP1 (0.54) LAP3ANPEPMMEECE1ACP3
SCHEMBL3098284 0.80 FPR2 (0.52) HPGDSEPHX1
SCHEMBL5597677 0.80 EPHX1 (0.51) MMEHPGDSEPHX1
SCHEMBL5597679 0.80 EPHX1 (0.51) MMEHPGDSEPHX1
SCHEMBL8843830 0.80 EPHX1 (0.51) ANPEPHPGDSEPHX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100247463-A1 N-(PHOSPHONOALKYL)-AMINO ACIDS, DERIVATIVES THEREOF AND COMPOSITIONS AND METHODS OF USE YU RUEY J 2010-09-30 — — US claimed