Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 5/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | KDM6B | O15054 | 3/20 | 0.47 |
| ▸ | KDM5C | P41229 | 3/20 | 0.47 |
| ▸ | KDM2A | Q9Y2K7 | 3/20 | 0.47 |
| ▸ | KDM3A | Q9Y4C1 | 3/20 | 0.47 |
| ▸ | KDM4A | O75164 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | KDM5A | P29375 | 2/20 | 0.47 |
| ▸ | KDM5B | Q9UGL1 | 2/20 | 0.47 |
| ▸ | TET3 | O43151 | 1/20 | 0.47 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | ASPH | Q12797 | 1/20 | 0.47 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.47 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.47 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.47 |
| ▸ | KDM7A | Q6ZMT4 | 1/20 | 0.47 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.47 |
| ▸ | TET1 | Q8NFU7 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3942944 | 1.00 | KDM4C (0.47) | KDM4CKDM4EKDM6BKDM5CKDM2A | |
| SCHEMBL20008477 | 0.86 | MYC (0.46) | KDM5CKDM5BLMNASMN1; SMN2RAF1 | |
| SCHEMBL25701324 | 0.86 | RAF1 (0.41) | LMNASMN1; SMN2RAF1BRAFNPC1 | |
| SCHEMBL1759647 | 0.81 | LMNA (0.62) | KDM4CKDM4EKDM6BKDM5CKDM2A | |
| SCHEMBL25225199 | 0.80 | JMJD6 (0.48) | ALDH1A1RAF1BRAFJMJD6 | |
| SCHEMBL29537110 | 0.80 | JMJD6 (0.48) | ALDH1A1RAF1BRAFJMJD6 | |
| SCHEMBL16094544 | 0.80 | KDM4C (0.53) | KDM4CKDM4EKDM6BKDM5CKDM2A | |
| SCHEMBL16095006 | 0.80 | KDM4C (0.53) | KDM4CKDM4EKDM6BKDM5CKDM2A | |
| SCHEMBL30069005 | 0.80 | KDM4C (0.53) | KDM4CKDM4EKDM6BKDM5CKDM2A | |
| SCHEMBL30893039 | 0.78 | KDM4C (0.52) | KDM4CKDM4EKDM6BKDM5CKDM2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118159537-A | 6-Aza-quinoline derivatives and related uses | 黑钻治疗公司 | 2024-06-07 | — | — | CN | disclosed |