Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MYC | P01106 | 1/20 | 0.46 |
| ▸ | RAF1 | P04049 | 15/20 | 0.41 |
| ▸ | BRAF | P15056 | 13/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | KDM4B | O94953 | 1/20 | 0.39 |
| ▸ | KDM5C | P41229 | 1/20 | 0.39 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3942944 | 0.86 | KDM4C (0.47) | RAF1BRAFLMNANPC1RAB9A | |
| SCHEMBL31032276 | 0.86 | KDM4C (0.47) | RAF1BRAFLMNANPC1RAB9A | |
| SCHEMBL25701324 | 0.84 | RAF1 (0.41) | RAF1BRAFLMNANPC1RAB9A | |
| SCHEMBL11347447 | 0.82 | LMNA (0.56) | MYCLMNANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL17526117 | 0.80 | LMNA (0.44) | MYCLMNANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL20008492 | 0.79 | LMNA (0.43) | MYCRAF1BRAFLMNANPC1 | |
| SCHEMBL25225199 | 0.79 | JMJD6 (0.48) | RAF1BRAF | |
| SCHEMBL29537110 | 0.79 | JMJD6 (0.48) | RAF1BRAF | |
| SCHEMBL22169023 | 0.76 | ALDH1A1 (0.44) | MYCLMNANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9307984 | 0.76 | LMNA (0.42) | MYCLMNANPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3299367-A1 | BIARYL AMIDE COMPOUNDS AS KINASE INHIBITORS | Novartis AG (CH) | 2018-03-28 | — | — | EP | disclosed |