Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 1.00 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.54 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.49 |
| ▸ | HTR2A | P28223 | 1/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12359956 | 0.93 | SIGMAR1 (0.87) | SIGMAR1TMEM97SLC6A2HTR2ASLC6A4 | |
| SCHEMBL12124424 | 0.91 | SIGMAR1 (0.83) | SIGMAR1TMEM97 | |
| SCHEMBL12124710 | 0.88 | SIGMAR1 (0.77) | SIGMAR1 | |
| SCHEMBL12124423 | 0.83 | SIGMAR1 (0.71) | SIGMAR1TMEM97 | |
| SCHEMBL21616830 | 0.78 | SIGMAR1 (0.63) | SIGMAR1TMEM97 | |
| SCHEMBL12124486 | 0.78 | SLC6A2 (0.82) | SIGMAR1SLC6A2HTR2ASLC6A4SLC6A3 | |
| SCHEMBL12124611 | 0.77 | SIGMAR1 (0.63) | SIGMAR1TMEM97 | |
| SCHEMBL10392904 | 0.77 | ALDH1A1 (0.63) | SIGMAR1 | |
| SCHEMBL12124484 | 0.77 | SIGMAR1 (1.00) | SIGMAR1 | |
| SCHEMBL2587520 | 0.75 | MIF (0.64) | SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024163956-A2 | SIGMA RECEPTOR LIGAND COMPOUNDS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2024-08-08 | — | — | WO | disclosed |