Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 6/20 | 0.39 |
| ▸ | RAB9A | P51151 | 6/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.36 |
| ▸ | LCK | P06239 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31033247 | 0.88 | MAOA (0.43) | MAOAIDO1MAOBNPC1RAB9A | |
| SCHEMBL31033260 | 0.88 | RAB9A (0.49) | MAOAIDO1MAOBNPC1RAB9A | |
| SCHEMBL31011136 | 0.87 | MAOA (0.51) | MAOAIDO1MAOBNPC1RAB9A | |
| SCHEMBL31033250 | 0.84 | MAOA (0.58) | MAOAIDO1MAOBNPC1RAB9A | |
| SCHEMBL31033254 | 0.83 | MAOA (0.44) | MAOAIDO1MAOBRAB9AKDM4E | |
| SCHEMBL31033253 | 0.79 | MAOA (0.66) | MAOAIDO1MAOBNPC1RAB9A | |
| SCHEMBL31091517 | 0.76 | MAOA (0.54) | MAOAIDO1MAOBNPC1RAB9A | |
| SCHEMBL31011135 | 0.74 | MAOA (0.51) | MAOAIDO1MAOBNPC1RAB9A | |
| SCHEMBL31033248 | 0.71 | MAOA (0.58) | MAOAIDO1MAOBNPC1RAB9A | |
| SCHEMBL31011137 | 0.69 | MAOA (0.68) | MAOAIDO1MAOBNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118420557-B | Zhu Gongjun acid analogue, and preparation method and application thereof | 济南爱思医药科技有限公司 | 2024-10-11 | — | — | CN | disclosed |
| CN-118420557-A | Zhu Gongjun acid analogue, and preparation method and application thereof | 济南爱思医药科技有限公司 | 2024-08-02 | — | — | CN | disclosed |