SCHEMBL31033253

SCHEMBL31033253

CC(C)(C)OC(=O)c1c2nc3c(C(=O)OC(C)(C)C)cccc3oc-2cc(=O)c1N

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 2/20 0.66
IDO1 P14902 1/20 0.66
MAOB P27338 1/20 0.66
AR P10275 2/20 0.38
TOP2A P11388 2/20 0.35
TNKS O95271 1/20 0.33
MAPT P10636 6/20 0.33
HPGD P15428 4/20 0.33
MEN1 O00255 4/20 0.33
ALDH1A1 P00352 4/20 0.33
KMT2A Q03164 4/20 0.33
CYP2C9 P11712 3/20 0.33
CYP2C19 P33261 3/20 0.33
BLM P54132 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
RAB9A P51151 2/20 0.33
NPC1 O15118 1/20 0.33
GMNN O75496 1/20 0.33
RAF1 P04049 1/20 0.33
TP53 P04637 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31011133 0.87 IDO1 (0.69) MAOAIDO1MAOBTOP2ATNKS
SCHEMBL31091517 0.87 MAOA (0.54) MAOAIDO1MAOBARTNKS
SCHEMBL31011136 0.85 MAOA (0.51) MAOAIDO1MAOBTNKSMAPT
Cinnabarinic Acid SCHEMBL11888793 0.80 MAOA (1.00) MAOAIDO1MAOBARTOP2A
SCHEMBL31033255 0.80 MAOB (0.64) MAOAIDO1MAOBMAPTHPGD
SCHEMBL14680386 0.79 MAOA (0.85) MAOAIDO1MAOBARTOP2A
SCHEMBL31033254 0.79 MAOA (0.44) MAOAIDO1MAOBMAPTHPGD
SCHEMBL31033252 0.79 MAOA (0.44) MAOAIDO1MAOBMAPTHPGD
SCHEMBL31033247 0.78 MAOA (0.43) MAOAIDO1MAOBMAPTHPGD
SCHEMBL31011134 0.76 IDO1 (0.56) MAOAIDO1MAOBTNKSMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118420557-B Zhu Gongjun acid analogue, and preparation method and application thereof 济南爱思医药科技有限公司 2024-10-11 CN disclosed
CN-118420557-A Zhu Gongjun acid analogue, and preparation method and application thereof 济南爱思医药科技有限公司 2024-08-02 CN disclosed