Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.64 |
| ▸ | IDO1 | P14902 | 1/20 | 0.64 |
| ▸ | MAOA | P21397 | 1/20 | 0.64 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.39 |
| ▸ | FBP1 | P09467 | 2/20 | 0.39 |
| ▸ | KDM5A | P29375 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31091516 | 0.89 | MAOB (0.54) | MAOBIDO1MAOAAKR1B1POLB | |
| SCHEMBL31011133 | 0.81 | IDO1 (0.69) | MAOBIDO1MAOAKMT2AMEN1 | |
| SCHEMBL31033253 | 0.80 | MAOA (0.66) | MAOBIDO1MAOAPOLBKMT2A | |
| Cinnabarinic Acid SCHEMBL29631673 | 0.79 | MAOA (1.00) | MAOBIDO1MAOAPOLBKMT2A | |
| SCHEMBL14680386 | 0.76 | MAOA (0.85) | MAOBIDO1MAOAPOLBKMT2A | |
| SCHEMBL31014195 | 0.76 | MAOB (0.45) | MAOBIDO1MAOAALDH1A1BCHE | |
| SCHEMBL31091523 | 0.75 | IDO1 (0.54) | MAOBIDO1MAOAKMT2AMEN1 | |
| SCHEMBL19914213 | 0.74 | ALDH1A1 (0.51) | MAOBPOLBKMT2AMEN1ALDH1A1 | |
| SCHEMBL31091514 | 0.74 | MAOB (0.53) | MAOBIDO1MAOAALDH1A1TDP1 | |
| SCHEMBL31091511 | 0.74 | MAOB (0.53) | MAOBIDO1MAOAKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118420557-B | Zhu Gongjun acid analogue, and preparation method and application thereof | 济南爱思医药科技有限公司 | 2024-10-11 | — | — | CN | disclosed |
| CN-118420557-A | Zhu Gongjun acid analogue, and preparation method and application thereof | 济南爱思医药科技有限公司 | 2024-08-02 | — | — | CN | disclosed |