SCHEMBL31033296

SCHEMBL31033296

CNCc1c(C)oc2c(OC3Cc4ccccc4N3C(=O)OC(C)(C)C)cccc12

nearest known ligand 0.37

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.37
KDM4E B2RXH2 3/20 0.37
GAA P10253 2/20 0.37
TSHR P16473 2/20 0.37
NPSR1 Q6W5P4 1/20 0.37
MAPK1 P28482 1/20 0.35
RAB9A P51151 2/20 0.34
NAMPT P43490 1/20 0.34
KMT2A Q03164 1/20 0.33
LMNA P02545 2/20 0.32
MAPT P10636 1/20 0.32
HPGD P15428 1/20 0.32
HSD17B10 Q99714 1/20 0.32
NPC1 O15118 1/20 0.32
PKM P14618 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
CCKBR P32239 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31033286 0.82 ALDH1A1 (0.40) ALDH1A1TSHRKMT2ALMNA
SCHEMBL22010480 0.73 GPR119 (0.37) LMNAMAPT
SCHEMBL31033306 0.73 GPR119 (0.37) LMNAMAPT
SCHEMBL8522019 0.67 BCHE (0.46) ALDH1A1MAPK1NPC1
SCHEMBL31092820 0.64 ACE (0.55)
SCHEMBL29545684 0.64 ACE (0.55)
SCHEMBL927332 0.64 ACE (0.55)
SCHEMBL705456 0.64 ACE (0.55)
SCHEMBL3702462 0.64 ACE (0.55)
SCHEMBL29443087 0.64 ACE (0.55)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113272302-B Antibiotic compound, method for producing same, pharmaceutical composition containing same, and use thereof 德彪药业国际股份公司 2024-08-13 CN disclosed