Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO2 | P16083 | 6/20 | 0.57 |
| ▸ | POLB | P06746 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | G6PD | P11413 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | CASP6 | P55212 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.46 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.46 |
| ▸ | HPGDS | O60760 | 2/20 | 0.45 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.42 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1039998 | 1.00 | NQO2 (0.57) | NQO2POLBMAPTRAB9ANPC1 | |
| SCHEMBL621981 | 0.88 | NQO2 (0.58) | NQO2POLBMAPTRAB9ANPC1 | |
| SCHEMBL1039184 | 0.79 | NQO2 (0.56) | NQO2POLBMAPTRAB9ANPC1 | |
| SCHEMBL13666134 | 0.79 | NQO2 (0.56) | NQO2POLBMAPTRAB9ANPC1 | |
| SCHEMBL30363708 | 0.77 | NQO2 (0.88) | NQO2POLBMAPTRAB9ANPC1 | |
| SCHEMBL3731976 | 0.77 | NQO2 (0.88) | NQO2POLBMAPTRAB9ANPC1 | |
| SCHEMBL11842508 | 0.77 | ALDH1A1 (0.50) | NQO2POLBMAPTRAB9ANPC1 | |
| SCHEMBL3966324 | 0.77 | NQO2 (0.67) | NQO2POLBMAPTRAB9ANPC1 | |
| SCHEMBL20597249 | 0.76 | DCPS (0.48) | MAPTRAB9ANPC1LMNAMEN1 | |
| SCHEMBL2320859 | 0.76 | ADORA3 (0.41) | NQO2RAB9ANPC1LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024148272-A1 | AZA BICYCLIC HETEROARYL DERIVATIVES AS ECTONUCLEOTIDE PYROPHOSPHATASE PHOSPHODIESTERASE 1 INHIBITORS | RIBOSCIENCE LLC (US) | 2024-07-11 | — | — | WO | disclosed |