Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 5/20 | 0.41 |
| ▸ | CA2 | P00918 | 5/20 | 0.41 |
| ▸ | CA4 | P22748 | 5/20 | 0.41 |
| ▸ | CA6 | P23280 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | HBB | P68871 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10052945 | 0.98 | CA1 (0.44) | CA1CA2CA4CA6KDM4E | |
| SCHEMBL5918112 | 0.84 | CA1 (0.48) | CA1CA2CA4CA6KDM4E | |
| SCHEMBL6979304 | 0.82 | TSHR (0.41) | CA1CA2CA4CA6KDM4E | |
| SCHEMBL6976158 | 0.82 | CA1 (0.38) | CA1CA2CA4CA6KDM4E | |
| SCHEMBL7702898 | 0.77 | CA1 (0.46) | CA1CA2CA4CA6KDM4E | |
| SCHEMBL14577664 | 0.77 | CA1 (0.42) | CA1CA2CA4CA6KDM4E | |
| SCHEMBL12976022 | 0.75 | CA2 (0.38) | CA1CA2CA4CA6KDM4E | |
| SCHEMBL10052944 | 0.75 | CA2 (0.38) | CA1CA2CA4CA6KDM4E | |
| SCHEMBL19970916 | 0.73 | — | — | |
| SCHEMBL5918173 | 0.73 | CA1 (0.40) | CA1CA2CA4CA6KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100255051-A1 | POLYKETAL POLYMERS, AND METHODS OF MAKING AND USING SAME | BENZ MICHAEL ERIC | 2010-10-07 | — | — | US | disclosed |
| US-7741375-B2 | Polyketal polymers, and methods of making and using same | MEDTRONIC, INC (US) | 2010-06-22 | — | — | US | disclosed |
| EP-1984421-A1 | POLYKETAL POLYMERS, AND METHODS OF MAKING AND USING SAME | Medtronic, Inc. (US) | 2008-10-29 | — | — | EP | disclosed |
| US-20070265355-A1 | Polyketal polymers, and methods of making and using same | MEDTRONIC, INC. | 2007-11-15 | — | — | US | disclosed |
| WO-2007098041-A1 | POLYKETAL POLYMERS, AND METHODS OF MAKING AND USING SAME | MEDTRONIC, INC. (US) | 2007-08-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070265355-A1 | Polyketal polymers, and methods of making and using same | PKLR, PBK, PKM | CA1 2998/4885CA2 3667/4885CA4 2181/4885 |
| US-20100255051-A1 | POLYKETAL POLYMERS, AND METHODS OF MAKING AND USING SAME | PKLR, PBK, PKM | CA1 2998/4885CA2 3667/4885CA4 2181/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.