Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APLNR | P35414 | 3/20 | 0.56 |
| ▸ | TAS2R14 | Q9NYV8 | 14/20 | 0.53 |
| ▸ | PTGES | O14684 | 1/20 | 0.48 |
| ▸ | TAS2R8 | Q9NYW2 | 1/20 | 0.48 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.48 |
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
| ▸ | CNR2 | P34972 | 1/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29671340 | 0.90 | APLNR (0.61) | APLNRTAS2R14PTGESTAS2R8CXCR3 | |
| SCHEMBL31172639 | 0.86 | APLNR (0.56) | APLNRTAS2R14PTGESTAS2R8CXCR3 | |
| SCHEMBL31149695 | 0.83 | APLNR (0.54) | APLNRTAS2R14PTGESTAS2R8CXCR3 | |
| SCHEMBL29665752 | 0.83 | HDAC6 (0.57) | APLNRTAS2R14HDAC11HDAC8HDAC6 | |
| SCHEMBL31149696 | 0.83 | APLNR (0.54) | APLNRTAS2R14PTGESTAS2R8CXCR3 | |
| SCHEMBL25578370 | 0.82 | TAS2R14 (0.55) | APLNRTAS2R14PTGESTAS2R8CXCR3 | |
| SCHEMBL31034596 | 0.82 | APLNR (0.52) | APLNRTAS2R14PTGESTAS2R8CXCR3 | |
| SCHEMBL31034592 | 0.82 | APLNR (0.52) | APLNRTAS2R14PTGESTAS2R8CXCR3 | |
| SCHEMBL31034527 | 0.81 | TAS2R14 (0.60) | APLNRTAS2R14PTGESTAS2R8CXCR3 | |
| SCHEMBL29665682 | 0.81 | APLNR (0.54) | APLNRTAS2R14PTGESTAS2R8CXCR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024175999-A2 | BENZENESULFONAMIDE DERIVATIVES AND USES THEREOF | DUNAD THERAPEUTICS LTD. (GB) | 2024-08-29 | — | — | WO | disclosed |