Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APLNR | P35414 | 2/20 | 0.52 |
| ▸ | TAS2R14 | Q9NYV8 | 11/20 | 0.52 |
| ▸ | PTGES | O14684 | 1/20 | 0.48 |
| ▸ | TAS2R8 | Q9NYW2 | 1/20 | 0.48 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.47 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31034592 | 1.00 | APLNR (0.52) | APLNRTAS2R14PTGESTAS2R8CXCR3 | |
| SCHEMBL29671340 | 0.89 | APLNR (0.61) | APLNRTAS2R14PTGESTAS2R8CXCR3 | |
| SCHEMBL31034590 | 0.85 | APLNR (0.50) | APLNRTAS2R14PTGESTAS2R8CXCR3 | |
| SCHEMBL31034527 | 0.83 | TAS2R14 (0.60) | APLNRTAS2R14PTGESTAS2R8CXCR3 | |
| SCHEMBL29665682 | 0.83 | APLNR (0.54) | APLNRTAS2R14PTGESTAS2R8CXCR3 | |
| SCHEMBL31034551 | 0.82 | APLNR (0.56) | APLNRTAS2R14PTGESTAS2R8CXCR3 | |
| SCHEMBL31034579 | 0.80 | HDAC6 (0.52) | APLNRTAS2R14PTGESTAS2R8CXCR3 | |
| SCHEMBL27020194 | 0.80 | TAS2R14 (0.59) | APLNRTAS2R14PTGESTAS2R8CXCR3 | |
| SCHEMBL24472769 | 0.79 | HDAC6 (0.77) | TAS2R14CXCR3HDAC6HDAC11HDAC8 | |
| SCHEMBL29671219 | 0.78 | APLNR (0.51) | APLNRTAS2R14PTGESTAS2R8CXCR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024175999-A2 | BENZENESULFONAMIDE DERIVATIVES AND USES THEREOF | DUNAD THERAPEUTICS LTD. (GB) | 2024-08-29 | — | — | WO | disclosed |