Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | PLEC | Q15149 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19792422 | 1.00 | NPC1 (0.32) | NPC1RAB9APTGDR2MAPK1HSD17B10 | |
| SCHEMBL671127 | 0.78 | PTGDR2 (0.33) | NPC1RAB9APTGDR2MAPK1HSD17B10 | |
| SCHEMBL30765098 | 0.77 | MEN1 (0.38) | NPC1RAB9APTGDR2MEN1ALDH1A1 | |
| SCHEMBL31394337 | 0.77 | NPC1 (0.33) | NPC1RAB9APTGDR2MAPK1HSD17B10 | |
| SCHEMBL1630992 | 0.77 | MEN1 (0.38) | NPC1RAB9APTGDR2MEN1ALDH1A1 | |
| SCHEMBL6687144 | 0.77 | DGAT1 (0.33) | — | |
| SCHEMBL24012991 | 0.75 | HDAC1 (0.34) | NPC1RAB9APTGDR2MAPK1HSD17B10 | |
| SCHEMBL29519110 | 0.75 | ADRB2 (0.35) | NPC1RAB9APTGDR2MAPK1HSD17B10 | |
| SCHEMBL31035450 | 0.75 | SHBG (0.34) | PTGDR2PYCR1ALDH1A1MAPT | |
| SCHEMBL1571123 | 0.75 | ADRB2 (0.35) | NPC1RAB9APTGDR2MAPK1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4680612-A1 | CHEMICAL COMPOUNDS | AN2 Therapeutics, Inc. (US) | 2026-01-21 | — | — | EP | disclosed |
| WO-2024192309-A1 | CHEMICAL COMPOUNDS | REACTIVE BIOSCIENCES, INC. (US) | 2024-09-19 | — | — | WO | disclosed |