SCHEMBL31035638

SCHEMBL31035638

COc1cccc(O[Si](c2ccccc2)(c2ccccc2)C(C)(C)C)c1C=O

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR6 P50406 1/20 0.36
TLR2 O60603 1/20 0.36
ERN1 O75460 1/20 0.36
TLR1 Q15399 1/20 0.36
TLR6 Q9Y2C9 1/20 0.36
ALDH1A1 P00352 1/20 0.35
ABCG2 Q9UNQ0 1/20 0.34
AMY1A P0DUB6 1/20 0.34
CA12 O43570 2/20 0.33
CA1 P00915 2/20 0.33
CA2 P00918 2/20 0.33
CA7 P43166 2/20 0.33
CA9 Q16790 2/20 0.33
CA14 Q9ULX7 2/20 0.33
CA4 P22748 1/20 0.33
NFE2L2 Q16236 5/20 0.33
FGFR1 P11362 2/20 0.33
TTR P02766 1/20 0.33
GAA P10253 1/20 0.33
NPC1 O15118 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5238358 0.84 ERN1 (0.41) HTR6ERN1ALDH1A1ABCG2FGFR1
SCHEMBL31035646 0.80 ERN1 (0.40) ERN1ALDH1A1NPC1MAPTRAB9A
SCHEMBL22032632 0.79 LMNA (0.46) TLR2ERN1TLR1TLR6ALDH1A1
SCHEMBL4423511 0.78 ALDH1A1 (0.55) ALDH1A1TTRNPC1LMNAMAPT
SCHEMBL30844046 0.77
SCHEMBL170690 0.76 ERN1 (0.55) TLR2ERN1TLR1TLR6ALDH1A1
SCHEMBL3256391 0.74 EPAS1 (0.36) ALDH1A1
SCHEMBL25282164 0.73 ERN1 (0.44) ERN1ALDH1A1MAPT
SCHEMBL7137746 0.72 MEN1 (0.36) ALDH1A1CA12CA1CA2CA7
SCHEMBL30108108 0.72 NR3C2 (0.40) NFE2L2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4680612-A1 CHEMICAL COMPOUNDS AN2 Therapeutics, Inc. (US) 2026-01-21 EP disclosed
WO-2024192309-A1 CHEMICAL COMPOUNDS REACTIVE BIOSCIENCES, INC. (US) 2024-09-19 WO disclosed