Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | GRIN2D | O15399 | 4/20 | 0.33 |
| ▸ | GRIN3B | O60391 | 4/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 4/20 | 0.33 |
| ▸ | GRIN2A | Q12879 | 4/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 4/20 | 0.33 |
| ▸ | GRIN2C | Q14957 | 4/20 | 0.33 |
| ▸ | GRIN3A | Q8TCU5 | 4/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.32 |
| ▸ | GUSB | P08236 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL534655 | 0.78 | HTT (0.40) | CYP3A4CHRM1ALOX15MAOATBXA2R | |
| SCHEMBL534618 | 0.78 | CYP3A4 (0.34) | CYP3A4CHRM1ALOX15MAOATBXA2R | |
| SCHEMBL3114113 | 0.78 | RPS6KA3 (0.37) | CYP3A4KDM4EALDH1A1ADORA3ADORA1 | |
| SCHEMBL18458869 | 0.77 | RECQL (0.33) | ALDH1A1ADORA3ADORA1 | |
| SCHEMBL19780464 | 0.75 | PARP1 (0.34) | ALDH1A1ADORA3ADORA1 | |
| SCHEMBL19780469 | 0.73 | PTGDR2 (0.38) | KDM4EPLAU | |
| SCHEMBL18458802 | 0.73 | PSMD14 (0.44) | ALOX15MAPK1KDM4EALDH1A1MEN1 | |
| SCHEMBL22542353 | 0.72 | KDM4E (0.44) | KDM4ECCR1CCR5CCR8ATM | |
| SCHEMBL3112415 | 0.71 | ALDH1A1 (0.42) | CYP3A4GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL1927585 | 0.70 | ALDH1A1 (0.32) | ALDH1A1CCR1CCR5CCR8MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2185520-B1 | FUNGICIDAL 2-ALKYLTHIO-2-QUINOLINYLOXY-ACETAMIDE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2012-12-26 | — | — | EP | disclosed |
| CN-101796030-B | Fungicidal 2-Alkylthio-2-quinolinyloxy-acetamide derivatives | SYNGENTA PARTICIPATIONS AG | 2012-08-22 | — | — | CN | disclosed |
| US-20100256183-A1 | FUNGICIDAL 2-ALKYLTHIO-2-QUINOLINYLOXY-ACETAMIDE DERIVATIVES | SYNGENTA CROP PROTECTION, INC. (US) | 2010-10-07 | — | — | US | disclosed |
| CN-101796030-A | Fungicidal 2-Alkylthio-2-quinolinyloxy-acetamide derivatives | SYNGENTA PARTICIPATIONS AG | 2010-08-04 | — | — | CN | disclosed |
| EP-2185520-A1 | FUNGICIDAL 2-ALKYLTHIO-2-QUINOLINYLOXY-ACETAMIDE DERIVATIVES | Sygenta Participations AG. (CH) | 2010-05-19 | — | — | EP | disclosed |
| WO-2009030469-A1 | FUNGICIDAL 2-ALKYLTHIO-2-QUINOLINYLOXY-ACETAMIDE DERITVATIVES | SYGENTA PARTICIPATIONS AG, (CH) | 2009-03-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100256183-A1 | FUNGICIDAL 2-ALKYLTHIO-2-QUINOLINYLOXY-ACETAMIDE DERIVATIVES | CYP1A2, AADAC, CYP51A1 | CYP3A4 35/4885CHRM1 1161/4885ALOX15 2257/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.