Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYCR1 | P32322 | 1/20 | 0.42 |
| ▸ | CES2 | O00748 | 2/20 | 0.42 |
| ▸ | CES1 | P23141 | 2/20 | 0.42 |
| ▸ | POLQ | O75417 | 1/20 | 0.42 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.40 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MLYCD | O95822 | 2/20 | 0.39 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.38 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.38 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.38 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.38 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31036190 | 0.86 | MLYCD (0.45) | CES2CES1POLQSRD5A2PTPN1 | |
| SCHEMBL31035930 | 0.86 | NR1H4 (0.46) | SRD5A2LIMK1LIMK2 | |
| SCHEMBL31035978 | 0.78 | MEN1 (0.54) | MEN1KMT2AMLYCD | |
| SCHEMBL31035948 | 0.76 | MAPT (0.49) | SRD5A2MEN1KMT2A | |
| SCHEMBL31035945 | 0.75 | MLYCD (0.52) | CES2CES1SRD5A2PTPN1MEN1 | |
| SCHEMBL31035814 | 0.74 | PYCR1 (0.56) | PYCR1POLQSRD5A2PTPN1GSK3B | |
| SCHEMBL24457331 | 0.74 | CES2 (0.39) | CES2CES1SRD5A2PTPN1GSK3B | |
| SCHEMBL7281175 | 0.72 | MLYCD (0.69) | CES2CES1PTPN1GSK3BMEN1 | |
| SCHEMBL31035984 | 0.71 | NR1H4 (0.46) | SRD5A2MLYCD | |
| SCHEMBL8484820 | 0.71 | LIMK1 (0.52) | LIMK1LIMK2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118459520-A | Spiramycin acylated derivative, preparation method, application and pharmaceutical composition | 赣江中药创新中心 | 2024-08-09 | — | — | CN | disclosed |