Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 5/20 | 0.59 |
| ▸ | IMPDH2 | P12268 | 9/20 | 0.57 |
| ▸ | IDO1 | P14902 | 1/20 | 0.45 |
| ▸ | TDO2 | P48775 | 1/20 | 0.45 |
| ▸ | PFKFB2 | O60825 | 1/20 | 0.43 |
| ▸ | PFKFB1 | P16118 | 1/20 | 0.43 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.43 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10575788 | 0.81 | ALDH1A1 (0.47) | XDHIMPDH2IDO1TDO2 | |
| SCHEMBL28427099 | 0.80 | XDH (0.61) | XDHIMPDH2 | |
| SCHEMBL28896300 | 0.76 | CA9 (0.67) | XDHIMPDH2 | |
| SCHEMBL29940860 | 0.76 | XDH (0.59) | XDHIMPDH2 | |
| SCHEMBL29940813 | 0.76 | CA9 (0.67) | XDHIMPDH2 | |
| SCHEMBL28896355 | 0.76 | XDH (0.59) | XDHIMPDH2 | |
| SCHEMBL28591584 | 0.75 | XDH (1.00) | XDH | |
| SCHEMBL10581101 | 0.75 | HTR1D (0.58) | IDO1TDO2 | |
| SCHEMBL16455426 | 0.74 | IMPDH2 (0.49) | XDHIMPDH2 | |
| SCHEMBL16455429 | 0.73 | IMPDH2 (0.59) | XDHIMPDH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118255685-A | Tricyclic compound, pharmaceutical composition and application thereof | 珂阑(上海)医药科技有限公司 | 2024-06-28 | — | — | CN | disclosed |