Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | DRD2 | P14416 | 3/20 | 0.54 |
| ▸ | DRD3 | P35462 | 2/20 | 0.54 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | DRD4 | P21917 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5570062 | 0.93 | TP53 (0.60) | KMT2AMEN1DRD2DRD3PAOX | |
| SCHEMBL15985650 | 0.86 | HDAC2 (0.51) | KMT2AMEN1DRD2DRD3PAOX | |
| SCHEMBL31036048 | 0.84 | MEN1 (0.53) | KMT2AMEN1DRD2DRD3TP53 | |
| SCHEMBL24412969 | 0.83 | TP53 (0.51) | PAOXTP53SMN1; SMN2SIGMAR1ALDH1A1 | |
| SCHEMBL24530659 | 0.83 | TP53 (0.56) | KMT2AMEN1DRD2DRD3TP53 | |
| SCHEMBL6196093 | 0.81 | SMN1; SMN2 (0.57) | KMT2AMEN1DRD2DRD3TP53 | |
| SCHEMBL3477552 | 0.81 | CASP2 (0.59) | PAOXTP53SMN1; SMN2USP2ALDH1A1 | |
| SCHEMBL8437935 | 0.80 | FAAH (0.55) | KMT2APAOXTP53SMN1; SMN2USP2 | |
| SCHEMBL23173790 | 0.79 | PAOX (0.51) | KMT2ADRD2DRD3PAOXTP53 | |
| SCHEMBL5230823 | 0.79 | SMN1; SMN2 (0.56) | KMT2AMEN1TP53SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118255685-A | Tricyclic compound, pharmaceutical composition and application thereof | 珂阑(上海)医药科技有限公司 | 2024-06-28 | — | — | CN | disclosed |