Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.66 |
| ▸ | ACE | P12821 | 4/20 | 0.62 |
| ▸ | ITGB2 | P05107 | 5/20 | 0.61 |
| ▸ | ICAM1 | P05362 | 5/20 | 0.61 |
| ▸ | ITGAL | P20701 | 5/20 | 0.61 |
| ▸ | ERAP2 | Q6P179 | 2/20 | 0.60 |
| ▸ | PPARG | P37231 | 1/20 | 0.60 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.60 |
| ▸ | TP53 | P04637 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | ECE1 | P42892 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28063888 | 0.93 | ALOX15 (0.64) | ALOX15ACEITGB2ICAM1ITGAL | |
| SCHEMBL16892772 | 0.90 | ALOX15 (0.65) | ALOX15ACEITGB2ICAM1ITGAL | |
| SCHEMBL29580749 | 0.90 | ALOX15 (0.65) | ALOX15ACEITGB2ICAM1ITGAL | |
| SCHEMBL31520113 | 0.89 | ACE (0.67) | ALOX15ACEITGB2ICAM1ITGAL | |
| SCHEMBL19051476 | 0.89 | ACE (0.67) | ALOX15ACEITGB2ICAM1ITGAL | |
| SCHEMBL4270030 | 0.87 | ERAP2 (0.67) | ALOX15ACEITGB2ICAM1ITGAL | |
| SCHEMBL11382213 | 0.87 | ALOX15 (0.70) | ALOX15ACEITGB2ICAM1ITGAL | |
| SCHEMBL11382215 | 0.87 | ALOX15 (0.70) | ALOX15ACEITGB2ICAM1ITGAL | |
| SCHEMBL11271279 | 0.86 | ACE (0.68) | ALOX15ACEITGB2ICAM1ITGAL | |
| SCHEMBL28401652 | 0.86 | ALOX15 (0.69) | ALOX15ACEITGB2ICAM1ITGAL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118255830-A | S1PR2 modulators and uses thereof | 北京昌平实验室 | 2024-06-28 | — | — | CN | disclosed |