SCHEMBL25258035

SCHEMBL25258035

Oc1cc2c(C(F)(F)F)nn(-c3ccccc3)c2c2ccccc12

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CYP11B2 P19099 2/20 0.43
▸ PTGS2 P35354 3/20 0.42
▸ SMN1; SMN2 Q16637 3/20 0.42
▸ PTGS1 P23219 3/20 0.41
▸ ALDH1A1 P00352 3/20 0.41
▸ MAPT P10636 3/20 0.41
▸ CYP2C9 P11712 2/20 0.41
▸ POLB P06746 2/20 0.41
▸ CYP19A1 P11511 1/20 0.41
▸ CYP11B1 P15538 1/20 0.41
▸ GAA P10253 1/20 0.41
▸ LMNA P02545 2/20 0.39
▸ NPSR1 Q6W5P4 1/20 0.39
▸ MEN1 O00255 3/20 0.38
▸ KMT2A Q03164 3/20 0.38
▸ CYP1A2 P05177 1/20 0.38
▸ HPGD P15428 1/20 0.38
▸ CYP2C19 P33261 1/20 0.38
▸ KDM4A O75164 1/20 0.37
▸ DCTPP1 Q9H773 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29402177 1.00 CYP11B2 (0.43) CYP11B2PTGS2SMN1; SMN2PTGS1ALDH1A1
SCHEMBL29405675 0.78 ATM (0.45) CYP11B2PTGS2SMN1; SMN2PTGS1ALDH1A1
SCHEMBL25251133 0.78 ATM (0.45) CYP11B2PTGS2SMN1; SMN2PTGS1ALDH1A1
SCHEMBL29405164 0.78 MAPK1 (0.53) SMN1; SMN2ALDH1A1MAPTPOLBLMNA
SCHEMBL25256531 0.78 MAPK1 (0.53) SMN1; SMN2ALDH1A1MAPTPOLBLMNA
SCHEMBL25301625 0.77 MAPT (0.46) PTGS2PTGS1ALDH1A1MAPTCYP2C9
SCHEMBL31037105 0.75 NPC1 (0.44) CYP11B2ALDH1A1CYP11B1LMNANPSR1
SCHEMBL25263172 0.75 ALDH1A1 (0.42) SMN1; SMN2ALDH1A1GAALMNAKMT2A
SCHEMBL25258027 0.75 ALDH1A1 (0.39) ALDH1A1MAPTGAALMNAKMT2A
SCHEMBL29405633 0.75 ALDH1A1 (0.42) SMN1; SMN2ALDH1A1GAALMNAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12570613-B2 Imidazoquinoline or benzoindazolone compound and intermediate for preparing same LMITO THERAPEUTICS INC. (KR) 2026-03-10 — — US disclosed
US-20240034719-A1 IMIDAZOQUINOLINE OR BENZOINDAZOLONE COMPOUND AND INTERMEDIATE FOR PREPARING SAME LMITO THERAPEUTICS INC. (KR) 2024-02-01 — — US disclosed
EP-4212530-A1 IMIDAZOLQUINOLINE OR BENZOINDAZOLONE COMPOUND AND INTERMEDIATE FOR PREPARING SAME Lmito Therapeutics Inc. (KR) 2023-07-19 — — EP disclosed
CN-115956071-A Imidazoquinoline or benzindazolone compounds and intermediates for their preparation LMITO药业株式会社 2023-04-11 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240034719-A1 IMIDAZOQUINOLINE OR BENZOINDAZOLONE COMPOUND AND INTERMEDIATE FOR PREPARING SAME NQO1, NFE2L2, KEAP1 CYP11B2 20/4885PTGS2 322/4885SMN1; SMN2 1271/4885
US-12570613-B2 Imidazoquinoline or benzoindazolone compound and intermediate for preparing same NQO1, CBR1, NFE2L2 CYP11B2 8/4885PTGS2 416/4885SMN1; SMN2 1672/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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