SCHEMBL31037327

SCHEMBL31037327

O=C(NCCc1cccnc1)Nc1ccc(-c2ccc3cnccc3c2)c(C#Cc2ccc(F)cc2)c1

nearest known ligand 0.55

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ PRMT3 O60678 7/20 0.55
▸ IMPDH2 P12268 2/20 0.46
▸ NAMPT P43490 5/20 0.44
▸ LMNA P02545 1/20 0.42
▸ ROCK2 O75116 3/20 0.41
▸ ROCK1 Q13464 2/20 0.41
▸ F3 P13726 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31037302 0.90 NAMPT (0.51) PRMT3NAMPTLMNAROCK2ROCK1
SCHEMBL31037468 0.86 LMNA (0.44) PRMT3NAMPTLMNAROCK2ROCK1
SCHEMBL31037290 0.83 NAMPT (0.40) PRMT3NAMPTLMNAROCK2ROCK1
SCHEMBL31037286 0.82 LMNA (0.48) PRMT3NAMPTLMNA
SCHEMBL31037293 0.82 LMNA (0.48) PRMT3NAMPTLMNA
SCHEMBL31037336 0.82 NAMPT (0.42) PRMT3NAMPTLMNAROCK2
SCHEMBL31037281 0.82 ROCK2 (0.48) PRMT3NAMPTLMNAROCK2ROCK1
SCHEMBL31037447 0.81 ROCK2 (0.49) PRMT3NAMPTROCK2ROCK1
SCHEMBL31037269 0.80 ROCK2 (0.46) PRMT3NAMPTROCK2ROCK1
SCHEMBL31037371 0.79 NAMPT (0.48) PRMT3NAMPTROCK2ROCK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4663628-A1 NEW COMPOUND AND PHARMACEUTICAL COMPOSITION COMPRISING SAME Samjin Pharmaceutical Co., Ltd. (KR) 2025-12-17 — — EP disclosed
WO-2024166024-A1 NEW COMPOUND AND PHARMACEUTICAL COMPOSITION COMPRISING SAME 삼진제약주식회사 2024-08-15 — — WO disclosed
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