SCHEMBL31037286

SCHEMBL31037286

O=C(NCCc1cccnc1)Nc1ccc(I)c(C#Cc2ccc(F)cc2)c1

nearest known ligand 0.48

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ LMNA P02545 1/20 0.48
▸ NAMPT P43490 12/20 0.47
▸ PRMT3 O60678 1/20 0.46
▸ SMN1; SMN2 Q16637 1/20 0.44
▸ L3MBTL1 Q9Y468 1/20 0.44
▸ RAB9A P51151 2/20 0.43
▸ CNR1 P21554 2/20 0.42
▸ NPC1 O15118 1/20 0.42
▸ MAPT P10636 1/20 0.42
▸ KMT2A Q03164 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31037293 0.89 LMNA (0.48) LMNANAMPTPRMT3SMN1; SMN2L3MBTL1
SCHEMBL31037483 0.88 NAMPT (0.47) LMNANAMPTPRMT3KMT2A
SCHEMBL31037302 0.86 NAMPT (0.51) LMNANAMPTPRMT3SMN1; SMN2L3MBTL1
SCHEMBL31037328 0.86 NAMPT (0.46) LMNANAMPTPRMT3SMN1; SMN2L3MBTL1
SCHEMBL31037498 0.85 LMNA (0.44) LMNANAMPTPRMT3SMN1; SMN2L3MBTL1
SCHEMBL31037468 0.83 LMNA (0.44) LMNANAMPTPRMT3SMN1; SMN2L3MBTL1
SCHEMBL31037322 0.83 HDAC2 (0.43) LMNANAMPTPRMT3SMN1; SMN2L3MBTL1
SCHEMBL31037327 0.82 PRMT3 (0.55) LMNANAMPTPRMT3
SCHEMBL31037254 0.82 NAMPT (0.46) LMNANAMPTPRMT3SMN1; SMN2L3MBTL1
SCHEMBL31037301 0.81 NAMPT (0.50) LMNANAMPTPRMT3RAB9ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4663628-A1 NEW COMPOUND AND PHARMACEUTICAL COMPOSITION COMPRISING SAME Samjin Pharmaceutical Co., Ltd. (KR) 2025-12-17 — — EP disclosed
WO-2024166024-A1 NEW COMPOUND AND PHARMACEUTICAL COMPOSITION COMPRISING SAME 삼진제약주식회사 2024-08-15 — — WO disclosed
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