Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR3 | P49682 | 20/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3097343 | 0.89 | CXCR3 (0.48) | CXCR3CYP3A4 | |
| SCHEMBL3098080 | 0.88 | CXCR3 (0.49) | CXCR3CYP3A4 | |
| SCHEMBL7021043 | 0.84 | CXCR3 (0.62) | CXCR3CYP3A4 | |
| SCHEMBL433440 | 0.83 | CXCR3 (0.71) | CXCR3CYP3A4 | |
| SCHEMBL13151350 | 0.82 | CXCR3 (0.84) | CXCR3CYP3A4 | |
| SCHEMBL3103733 | 0.82 | CXCR3 (0.84) | CXCR3CYP3A4 | |
| SCHEMBL18092522 | 0.81 | CXCR3 (0.73) | CXCR3CYP3A4 | |
| SCHEMBL3098073 | 0.79 | CXCR3 (0.55) | CXCR3 | |
| SCHEMBL16209820 | 0.76 | CXCR3 (0.73) | CXCR3CYP3A4 | |
| SCHEMBL7151983 | 0.75 | CXCR3 (0.59) | CXCR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7799795-B2 | Aryl nitrile compounds and compositions and their uses in treating inflammatory and related disorders | AMGEN INC. (US) | 2010-09-21 | — | — | US | claimed |