Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR3 | P49682 | 20/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL433440 | 0.94 | CXCR3 (0.71) | CXCR3CYP3A4 | |
| SCHEMBL16209820 | 0.87 | CXCR3 (0.73) | CXCR3CYP3A4 | |
| SCHEMBL18092522 | 0.84 | CXCR3 (0.73) | CXCR3CYP3A4 | |
| SCHEMBL3103736 | 0.84 | CXCR3 (0.60) | CXCR3CYP3A4 | |
| SCHEMBL5833103 | 0.82 | CXCR3 (0.89) | CXCR3CYP3A4 | |
| SCHEMBL27015148 | 0.82 | CXCR3 (0.89) | CXCR3CYP3A4 | |
| Trifluoroacetic Acid SCHEMBL7020020 | 0.81 | CXCR3 (0.53) | CXCR3 | |
| SCHEMBL29386766 | 0.77 | CXCR3 (1.00) | CXCR3CYP3A4 | |
| SCHEMBL335753 | 0.77 | CXCR3 (1.00) | CXCR3CYP3A4 | |
| SCHEMBL433439 | 0.77 | CXCR3 (1.00) | CXCR3CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1343505-A1 | CXCR3 ANTAGONISTS | Tularik Inc. (US) | 2003-09-17 | — | — | EP | disclosed |
| WO-2002083143-A1 | CXCR3 ANTAGONISTS | TULARIK INC. (US) | 2002-10-24 | — | — | WO | disclosed |