Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | MARS2 | Q96GW9 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.46 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.44 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.44 |
| ▸ | RPLP1 | P05386 | 1/20 | 0.43 |
| ▸ | RPLP0 | P05388 | 1/20 | 0.43 |
| ▸ | RPS17 | P08708 | 1/20 | 0.43 |
| ▸ | RPSA | P08865 | 1/20 | 0.43 |
| ▸ | RPS2 | P15880 | 1/20 | 0.43 |
| ▸ | RPL35A | P18077 | 1/20 | 0.43 |
| ▸ | RPL7 | P18124 | 1/20 | 0.43 |
| ▸ | RPL17 | P18621 | 1/20 | 0.43 |
| ▸ | RPS4Y1 | P22090 | 1/20 | 0.43 |
| ▸ | RPS3 | P23396 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14393697 | 0.86 | LMNA (0.48) | LMNAALDH1A1TSHRSMN1; SMN2CYP3A4 | |
| SCHEMBL13649416 | 0.86 | LMNA (0.48) | LMNAALDH1A1TSHRSMN1; SMN2CYP3A4 | |
| SCHEMBL14393834 | 0.86 | LMNA (0.48) | LMNAALDH1A1TSHRSMN1; SMN2CYP3A4 | |
| SCHEMBL9836784 | 0.84 | ALDH1A1 (0.65) | LMNAALDH1A1TSHRSMN1; SMN2CYP3A4 | |
| SCHEMBL23272194 | 0.84 | MEN1 (0.43) | LMNAALDH1A1TSHRSMN1; SMN2CYP3A4 | |
| SCHEMBL23272197 | 0.84 | MEN1 (0.43) | LMNAALDH1A1TSHRSMN1; SMN2CYP3A4 | |
| SCHEMBL18796524 | 0.83 | TACR1 (0.43) | LMNATSHRROCK2ROCK1L3MBTL1 | |
| SCHEMBL14338229 | 0.83 | TSHR (0.52) | LMNAALDH1A1TSHRSMN1; SMN2CYP3A4 | |
| SCHEMBL14338191 | 0.83 | TSHR (0.52) | LMNAALDH1A1TSHRSMN1; SMN2CYP3A4 | |
| SCHEMBL12862945 | 0.83 | TSHR (0.52) | LMNAALDH1A1TSHRSMN1; SMN2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4658667-A1 | CYCLIC PEPTIDES FOR INHIBITING TNF RECEPTOR 1 ACTIVITY | Merck Sharp & Dohme LLC (US) | 2025-12-10 | — | — | EP | disclosed |
| WO-2024163691-A1 | CYCLIC PEPTIDES FOR INHIBITING TNF RECEPTOR 1 ACTIVITY | MERCK SHARP & DOHME LLC (US) | 2024-08-08 | — | — | WO | disclosed |