Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.65 |
| ▸ | LMNA | P02545 | 3/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.65 |
| ▸ | TSHR | P16473 | 2/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.65 |
| ▸ | MARS2 | Q96GW9 | 1/20 | 0.65 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.65 |
| ▸ | RPLP1 | P05386 | 1/20 | 0.59 |
| ▸ | RPLP0 | P05388 | 1/20 | 0.59 |
| ▸ | RPS17 | P08708 | 1/20 | 0.59 |
| ▸ | RPSA | P08865 | 1/20 | 0.59 |
| ▸ | RPS2 | P15880 | 1/20 | 0.59 |
| ▸ | RPL35A | P18077 | 1/20 | 0.59 |
| ▸ | RPL7 | P18124 | 1/20 | 0.59 |
| ▸ | RPL17 | P18621 | 1/20 | 0.59 |
| ▸ | RPS4Y1 | P22090 | 1/20 | 0.59 |
| ▸ | RPS3 | P23396 | 1/20 | 0.59 |
| ▸ | RPS12 | P25398 | 1/20 | 0.59 |
| ▸ | RPL13 | P26373 | 1/20 | 0.59 |
| ▸ | RPL10 | P27635 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14338229 | 0.85 | TSHR (0.52) | ALDH1A1LMNACYP3A4TSHRSMN1; SMN2 | |
| SCHEMBL14338193 | 0.85 | TSHR (0.52) | ALDH1A1LMNACYP3A4TSHRSMN1; SMN2 | |
| SCHEMBL14338191 | 0.85 | TSHR (0.52) | ALDH1A1LMNACYP3A4TSHRSMN1; SMN2 | |
| SCHEMBL7091990 | 0.85 | LMNA (0.66) | ALDH1A1LMNACYP3A4TSHRSMN1; SMN2 | |
| SCHEMBL14568970 | 0.85 | LMNA (0.66) | ALDH1A1LMNACYP3A4TSHRSMN1; SMN2 | |
| SCHEMBL12862945 | 0.85 | TSHR (0.52) | ALDH1A1LMNACYP3A4TSHRSMN1; SMN2 | |
| SCHEMBL31037745 | 0.84 | LMNA (0.47) | ALDH1A1LMNACYP3A4TSHRSMN1; SMN2 | |
| SCHEMBL10777805 | 0.84 | LMNA (0.66) | ALDH1A1LMNACYP3A4TSHRSMN1; SMN2 | |
| SCHEMBL1753533 | 0.84 | LMNA (0.70) | ALDH1A1LMNACYP3A4TSHRSMN1; SMN2 | |
| SCHEMBL29651721 | 0.84 | LMNA (0.66) | ALDH1A1LMNACYP3A4TSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0272684-B1 | DERIVATIVES OF N-(METHYLSULPHONYLPHENYLETHYL)-2-PROPENAMIDES AND THEIR USE AS ANTIBIOTICS | ZAMBON S.p.A. (IT) | 1991-06-12 | — | — | EP | disclosed |
| US-4918095-A | Compositions with antibiotic activity and their use | ZAMBON S.P.A. (IT) | 1990-04-17 | — | — | US | disclosed |
| EP-0272684-A2 | Derivatives of N-(methylsulphonylphenylethyl)-2-propenamides and their use as antibiotics | ZAMBON S.p.A. (IT) | 1988-06-29 | — | — | EP | disclosed |