Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 9/20 | 0.50 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.35 |
| ▸ | HTR3A | P46098 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.34 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.34 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.34 |
| ▸ | NOS3 | P29474 | 1/20 | 0.34 |
| ▸ | NOS2 | P35228 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19480897 | 0.79 | ADORA2A (0.39) | CYP1A2CYP2C19ALDH1A1POLBMDM2 | |
| SCHEMBL19817434 | 0.76 | NOTUM (0.50) | NOTUMEGLN2CYP1A2CYP2C9CHRNB2 | |
| SCHEMBL29818411 | 0.76 | NOS3 (0.39) | CYP1A2CYP2C19ALDH1A1POLBMDM2 | |
| SCHEMBL21439781 | 0.75 | PRMT6 (0.42) | CYP1A2MAOACYP2C19ALDH1A1POLB | |
| SCHEMBL9945328 | 0.74 | ALDH1A1 (0.57) | NOTUMEGLN2CYP1A2CYP2C9CHRNB2 | |
| SCHEMBL10688400 | 0.70 | NOTUM (0.50) | NOTUMEGLN2CYP1A2CYP2C9CHRNB2 | |
| SCHEMBL15081414 | 0.70 | NOTUM (0.43) | NOTUM | |
| SCHEMBL10685651 | 0.70 | NOTUM (0.62) | NOTUMEGLN2CYP1A2CYP2C9CHRNB2 | |
| SCHEMBL19822798 | 0.70 | NOTUM (0.50) | NOTUMEGLN2CYP1A2CYP2C9CHRNB2 | |
| SCHEMBL11181913 | 0.69 | ALDH1A1 (0.43) | CYP1A2CYP2C19ALDH1A1POLBNOS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114945571-B | Cyclic compounds and methods of use thereof | 薛定谔公司 | 2025-02-25 | — | — | CN | disclosed |
| CN-118451068-A | Tri-fused ring derivative inhibitor, preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2024-08-06 | — | — | CN | disclosed |