Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.52 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.52 |
| ▸ | LMNA | P02545 | 5/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.49 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | ALPL | P05186 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | XBP1 | P17861 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22126764 | 1.00 | ESR1 (0.52) | ESR1CYP19A1ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL13106657 | 0.90 | ALDH1A1 (0.53) | ESR1CYP19A1ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL22126773 | 0.80 | ALDH1A1 (0.53) | ALDH1A1LMNASMN1; SMN2HTTKDM4E | |
| SCHEMBL18424298 | 0.79 | BRPF1 (0.56) | LMNASMN1; SMN2HTTKMT2AMAPT | |
| SCHEMBL19260071 | 0.79 | CA1 (0.49) | — | |
| SCHEMBL13122383 | 0.79 | ALDH1A1 (0.58) | ESR1CYP19A1ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL3599576 | 0.78 | PKM (0.61) | ESR1CYP19A1ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL13106667 | 0.78 | SMN1; SMN2 (0.53) | ESR1ALDH1A1LMNASMN1; SMN2HTT | |
| SCHEMBL13106663 | 0.78 | CES1 (0.53) | ESR1CYP19A1ALDH1A1LMNAHTT | |
| SCHEMBL13106659 | 0.78 | SMN1; SMN2 (0.60) | ESR1ALDH1A1LMNASMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111479805-B | Therapeutic indazoles | 罗格斯新泽西州立大学 | 2024-08-13 | — | — | CN | disclosed |