Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 1/20 | 0.57 |
| ▸ | CTSB | P07858 | 1/20 | 0.57 |
| ▸ | CTSK | P43235 | 1/20 | 0.57 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | DPP4 | P27487 | 5/20 | 0.50 |
| ▸ | DPP7 | Q9UHL4 | 5/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.50 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.50 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | F13A1 | P00488 | 2/20 | 0.46 |
| ▸ | TGM2 | P21980 | 2/20 | 0.46 |
| ▸ | TGM1 | P22735 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31039731 | 1.00 | CTSL (0.57) | CTSLCTSBCTSKEPHX1ALDH1A1 | |
| SCHEMBL25222224 | 0.92 | CTSL (0.61) | CTSLCTSBCTSKEPHX1ALDH1A1 | |
| SCHEMBL27922032 | 0.82 | CTSL (0.63) | CTSLCTSBCTSKEPHX1ALDH1A1 | |
| SCHEMBL3489847 | 0.81 | CTSL (0.62) | CTSLCTSBCTSKEPHX1ALDH1A1 | |
| SCHEMBL18697562 | 0.81 | CTSL (0.62) | CTSLCTSBCTSKEPHX1ALDH1A1 | |
| SCHEMBL27922050 | 0.80 | CTSL (0.61) | CTSLCTSBCTSKEPHX1ALDH1A1 | |
| SCHEMBL27922046 | 0.80 | CTSL (0.61) | CTSLCTSBCTSKEPHX1ALDH1A1 | |
| SCHEMBL25203367 | 0.79 | HSD11B1 (0.60) | CTSLCTSBCTSKEPHX1ALDH1A1 | |
| SCHEMBL29255622 | 0.79 | CTSL (0.60) | CTSLCTSBCTSKEPHX1ALDH1A1 | |
| SCHEMBL132397 | 0.79 | EPHX1 (0.53) | CTSLCTSBCTSKEPHX1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4630417-A1 | NOVEL COMPOUNDS AS MODULATORS OF NLRP3 INHIBITION | F. Hoffmann-La Roche AG (CH) | 2025-10-15 | — | — | EP | disclosed |
| WO-2024121086-A1 | NOVEL COMPOUNDS AS MODULATORS OF NLRP3 INHIBITION | F. HOFFMANN-LA ROCHE AG (CH) | 2024-06-13 | — | — | WO | disclosed |