Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 1/20 | 0.62 |
| ▸ | CTSB | P07858 | 1/20 | 0.62 |
| ▸ | CTSK | P43235 | 1/20 | 0.62 |
| ▸ | DPP4 | P27487 | 6/20 | 0.59 |
| ▸ | DPP7 | Q9UHL4 | 6/20 | 0.59 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.59 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.59 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | HPN | P05981 | 2/20 | 0.49 |
| ▸ | ST14 | Q9Y5Y6 | 2/20 | 0.49 |
| ▸ | F13A1 | P00488 | 2/20 | 0.48 |
| ▸ | TGM2 | P21980 | 2/20 | 0.48 |
| ▸ | TGM1 | P22735 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22829637 | 0.96 | DPP4 (0.61) | CTSLCTSBCTSKDPP4DPP7 | |
| SCHEMBL3487634 | 0.96 | DPP4 (0.61) | CTSLCTSBCTSKDPP4DPP7 | |
| SCHEMBL3667335 | 0.92 | CTSL (0.68) | CTSLCTSBCTSKDPP4DPP7 | |
| SCHEMBL13740409 | 0.92 | CTSL (0.68) | CTSLCTSBCTSKDPP4DPP7 | |
| SCHEMBL3003867 | 0.92 | CTSL (0.68) | CTSLCTSBCTSKDPP4DPP7 | |
| SCHEMBL25203367 | 0.90 | HSD11B1 (0.60) | CTSLCTSBCTSKDPP4DPP7 | |
| SCHEMBL2551898 | 0.90 | DPP4 (0.62) | CTSLCTSBCTSKDPP4DPP7 | |
| SCHEMBL22469698 | 0.90 | DPP4 (0.54) | CTSLCTSBCTSKDPP4DPP7 | |
| SCHEMBL18956862 | 0.89 | CTSL (0.58) | CTSLCTSBCTSKDPP4DPP7 | |
| SCHEMBL22469041 | 0.88 | HSD11B1 (0.62) | CTSLCTSBCTSKDPP4DPP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240140933-A1 | OXOINDOLINE COMPOUND FOR THE TREATMENT OF INFLAMMATORY DISEASES OR CANCER | HOFFMANN-LA ROCHE INC. (US) | 2024-05-02 | — | — | US | disclosed |
| WO-2023159148-A2 | INHIBITORS OF NLRP3 | PTC THERAPEUTICS, INC. (US) | 2023-08-24 | — | — | WO | disclosed |
| US-20100056497-A1 | AMIDE DERIVATIVE | DAINIPPON SUMITOMO PHARMA CO., LTD (JP) | 2010-03-04 | — | — | US | disclosed |
| EP-2119702-A1 | AMIDE DERIVATIVE | Dainippon Sumitomo Pharma Co., Ltd. (JP) | 2009-11-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240140933-A1 | OXOINDOLINE COMPOUND FOR THE TREATMENT OF INFLAMMATORY DISEASES OR CANCER | IL1B, IL1A, IL1R1 | CTSL 2415/4885CTSB 1522/4885CTSK 2436/4885 |
| US-20100056497-A1 | AMIDE DERIVATIVE | REN, AGTR1, AGTR2 | CTSL 1269/4885CTSB 326/4885CTSK 1472/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.