Sugi Predict

Sugi Predict / Compounds / SCHEMBL310420

SCHEMBL310420

SCHEMBL310420

O=[N+]([O-])c1cc(Cl)cc(Cl)c1O

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ GPR35 Q9HC97 6/20 0.69
▸ ALDH1A1 P00352 4/20 0.54
▸ TSHR P16473 3/20 0.54
▸ MAPK1 P28482 2/20 0.53
▸ TTR P02766 2/20 0.53
▸ CYP3A4 P08684 2/20 0.52
▸ RECQL P46063 2/20 0.52
▸ HSD17B10 Q99714 2/20 0.52
▸ MAPT P10636 4/20 0.51
▸ MEN1 O00255 3/20 0.51
▸ KMT2A Q03164 3/20 0.51
▸ TDP1 Q9NUW8 3/20 0.51
▸ LMNA P02545 3/20 0.51
▸ HTT P42858 2/20 0.51
▸ KDM4E B2RXH2 2/20 0.47
▸ CYP1A2 P05177 1/20 0.47
▸ CYP2C9 P11712 1/20 0.47
▸ HPGD P15428 1/20 0.47
▸ ALOX15 P16050 1/20 0.47
▸ ALOX12 P18054 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6010796 0.89 GPR35 (0.63) GPR35ALDH1A1TSHRMAPK1TTR
SCHEMBL4172077 0.83 TTR (0.67) GPR35ALDH1A1MAPK1TTRRECQL
Niclofolan SCHEMBL29385615 0.83 GPR35 (0.57) GPR35ALDH1A1TSHRMAPK1TTR
Niclofolan SCHEMBL1498232 0.83 GPR35 (0.57) GPR35ALDH1A1TSHRMAPK1TTR
SCHEMBL2165473 0.82 GPR35 (1.00) GPR35ALDH1A1TSHRMAPK1TTR
SCHEMBL30807397 0.82 GPR35 (1.00) GPR35ALDH1A1TSHRMAPK1TTR
SCHEMBL103341 0.80 GPR35 (0.65) GPR35ALDH1A1MAPK1TTRCYP3A4
SCHEMBL4544555 0.80 GPR35 (0.74) GPR35ALDH1A1TSHRMAPK1TTR
SCHEMBL28325905 0.80 GPR35 (0.65) GPR35ALDH1A1TSHRMAPK1TTR
SCHEMBL4293562 0.80 GPR35 (0.65) GPR35ALDH1A1MAPK1TTRCYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 305 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119409575-A Method for preparing 2, 6-dichloro-4-nitrophenol or 2, 4-dichloro-6-nitrophenol with zero wastewater discharge 内蒙古齐晖药业有限公司 2025-02-11 — — CN claimed
CN-108059602-B Preparation method of pentachlorosalilamine intermediate 2-amino-4, 6-dichlorophenol organic solution 常州齐晖药业有限公司 2023-04-21 — — CN claimed
CN-115389685-A Method for detecting hydroxychlorozamide genotoxic impurities 常州齐晖药业有限公司 2022-11-25 — — CN claimed
US-7691899-B2 Urea oligomers, the preparation method thereof and pharmaceutical composition containing same CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2010-04-06 — — US claimed
US-7691807-B2 Hybrid oligomers, their preparation process and pharmaceutical compositions containing them CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) 2010-04-06 — — US claimed
EP-1919868-A2 NEW HYBRID OLIGOMERS. THEIR PREPARATION PROCESS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM The Centre National de la Recherche Scientifique (FR) 2008-05-14 — — EP claimed
EP-1289968-B1 CYCLIC UREA COMPOUNDS AND PREPARATION THEREOF CENTRE NAT RECH SCIENT (FR) 2008-02-20 — — EP claimed
EP-1432677-B1 NOVEL UREA OLIGOMERS, THE PREPARATION METHOD THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME CENTRE NAT RECH SCIENT (FR) 2008-02-13 — — EP claimed
US-7329708-B2 Functionalized poly(arylene ether) composition and method GENERAL ELECTRIC COMPANY (US) 2008-02-12 — — US claimed
WO-2006131833-A2 NEW HYBRID OLIGOMERS. THEIR PREPARATION PROCESS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2006-12-14 — — WO claimed
WO-2003029198-A1 NOVEL UREA OLIGOMERS, THE PREPARATION METHOD THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2003-04-10 — — WO claimed
EP-1289968-A1 CYCLIC UREA COMPOUNDS AND PREPARATION THEREOF Centre National De La Recherche Scientifique (FR) 2003-03-12 — — EP claimed
US-20020143191-A1 Novel stabilized activated derivatives of carbamic acid, their process of preparation and their use for the preparation of ureas UREKA SARL (FR) 2002-10-03 — — US claimed
WO-2001096318-A1 CYCLIC UREA COMPOUNDS AND PREPARATION THEREOF CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2001-12-20 — — WO claimed
EP-0251115-B1 METHOD FOR THE PRODUCTION OF BETA-HALOVINYL- AND BETA,BETA-DIHALOETHYLARYLKETONES BASF Aktiengesellschaft (DE) 1991-08-21 — — EP claimed
EP-0251115-A2 Method for the production of beta-halovinyl- and beta,beta-dihaloethylarylketones BASF Aktiengesellschaft (DE) 1988-01-07 — — EP claimed
EP-0065020-B1 STABILIZED THERMOSETTABLE ETHYLENICALLY UNSATURATED EPOXY ESTER RESIN COMPOSITIONS Dow Chemical Rheinwerk GmbH (DE) 1986-03-05 — — EP claimed
US-4413105-A CHLORONITROPHENOL POLYMERIZATION INHIBITOR THE DOW CHEMICAL COMPANY (US) 1983-11-01 — — US claimed
EP-0065020-A1 Stabilized thermosettable ethylenically unsaturated epoxy ester resin compositions Dow Chemical Rheinwerk GmbH (DE) 1982-11-24 — — EP claimed
US-4031249-A TREMATODES, NEMATODES, FASCIOLA SP ICI AUSTRALIA LIMITED (AU) 1977-06-21 — — US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020143191-A1 Novel stabilized activated derivatives of carbamic acid, their process of preparation and their use for the preparation of ureas CPS1, ACMSD, PROC GPR35 3748/4885ALDH1A1 3306/4885TSHR 4095/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.